2002
DOI: 10.1097/00007611-200295090-00010
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Primary Mediastinal Large B-cell Lymphoma

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“…It is a rapidly growing tumor that arises in the thymus and predominantly involves the mediastinum. It has a female preponderance (M:F = 1:2) and mainly affects young adults (median age 30–40 years) 1 . Patients clinically present with symptoms secondary to compression of intrathoracic structures and invasion of the lungs, pleura, and pericardium.…”
Section: Discussionmentioning
confidence: 99%
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“…It is a rapidly growing tumor that arises in the thymus and predominantly involves the mediastinum. It has a female preponderance (M:F = 1:2) and mainly affects young adults (median age 30–40 years) 1 . Patients clinically present with symptoms secondary to compression of intrathoracic structures and invasion of the lungs, pleura, and pericardium.…”
Section: Discussionmentioning
confidence: 99%
“…Diagnosis is usually by chest X ray, CT scan, and tissue biopsy with molecular biology B‐cell marker studies. The natural history of the disease is death if untreated 1,2,3 …”
Section: Discussionmentioning
confidence: 99%