Primary B-Cell lymphoma of the uterine cervix presenting with right ureter hydronephrosis: A case report

Abstract

Highlights Primary cervical B-cell lymphoma can mimic locally advanced cervical cancer. Primary cervical lymphoma should be suspected in women with normal Pap smear and rapidly growing tumor. Initial biopsies of primary gynecological lymphomas can be non-contributory. Treatment should include R-CHOP based chemotherapy with methotrexate for neuromeningeal prophylaxis. Fertility-sparing management should be offered to young patients diagnosed with primary cervical lymphoma.

Primary diffuse large B-Cell lymphoma of the uterine cervix with severe lower urinary tract Symptoms: A rare case report and review of the literature

“…Thus, routine cervical cytology smears or superficial tissue biopsy results may be prone to generating false negatives or missing the lesion in deeper sites. ( Del et al, 2020 , Chan et al, 2005 ) In this case, cervical cytology revealed atypical squamous cells of undetermined significance (ASCUS), while HPV and SCC tests were negative, suggesting abnormal lesions in the cervix. Due to the obvious lesion, biopsy samples were taken during gynecological examination.…”

Ultrasonographic diagnosis of a lymphomatous lymph node presumptively infiltrating the ureter causing hydronephrosis in a 3‐year‐old dog

“…Within both veterinary and human literature, the author was unable to find any reports of a separate neoplastic organ invading the tissues of the ureter, though some papers alluded to the possibility in humans 14 . In most cases where hydronephrosis was found secondary to a separate abdominal mass, it was due to compression of the ureter by the mass itself or associated fibrotic tissue 15–18 . Obstruction secondary to infiltrative disease was decided in this case with the appearance of the mass entering the ureter and extending distally into the UVJ where it was then visualized within the bladder.…”

“…14 In most cases where hydronephrosis was found secondary to a separate abdominal mass, it was due to compression of the ureter by the mass itself or associated fibrotic tissue. [15][16][17][18] Obstruction secondary to infiltrative disease was decided in this case with the appearance of the mass entering the ureter and extending distally into the UVJ where it was then visualized within the bladder. Had the UVJ not been affected, compression from adjacent lymphadenopathy could not have been definitively ruled out without advanced imaging and/or necropsy.…”

Lymphoma of the uterine cervix- a rare clinical presentation: A case report

“…Primary lymphomas of the female genital tract are extremely rare, representing 0.2-1.1% of extranodal NHL and less than 0.5% of total gynecological malignancies 5 .…”