Primary antiphospholipid syndrome with acute myocardial infarction recanalised by PTCA

Takeuchi, Susumu; Obayashi, Toshihiro; Toyama, Junji

doi:10.1136/hrt.79.1.96

Cited by 49 publications

(20 citation statements)

References 12 publications

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“…52 In those patients with myocardial infarction secondary to accelerated premature atherosclerosis, early intervention with primary angioplasty has an improved outcome over thrombolysis. 53 PTCA and stenting should be considered in spontaneous coronary artery dissection and myocardial bridging.…”

Section: Angioplastymentioning

confidence: 99%

Acute myocardial infarction in young adults: causes and management

Osula

Bell

Hornung

2002

Postgraduate Medical Journal

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The case report in this review illustrates an acute myocardial infarction in a young adult probably due to arterial thrombosis that can be attributed to a hypercoagulable state resulting from the nephrotic syndrome. Although rare, acute myocardial infarction should be considered in young adults presenting with chest pain. A detailed clinical history may help to identify the aetiology, and guide subsequent management, but diagnostic coronary angiography is essential. Careful risk factor modification and treatment of the underlying cause should reduce the incidence of recurrent cardiac events.

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Section: Angioplastymentioning

confidence: 99%

Acute myocardial infarction in young adults: causes and management

Osula

Bell

Hornung

2002

Postgraduate Medical Journal

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“…1 Recent evidence suggests that APS may also result in early atherosclerosis. 2 Several studies have suggested that antiphospholipid antibodies (aPL) may be associated with accelerated atherosclerosis in patients with APS. 3 4 The ankle-brachial index (ABI) is a simple, inexpensive, and non-invasive diagnostic test for lower extremity peripheral arterial disease.…”

mentioning

confidence: 99%

Prevalence of an abnormal ankle-brachial index in patients with primary antiphospholipid syndrome: preliminary data

Baron

Khamashta

Hughes³

et al. 2005

Annals of the Rheumatic Diseases

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Objectives: To evaluate the prevalence of abnormal anklebrachial indexes (ABIs), their relationship with other cardiovascular risk factors and/or the presence of antiphospholipid antibodies (aPL), and the clinical use of the ABI in patients with primary antiphospholipid syndrome (primary APS). Methods: An 8 MHz Doppler probe was used in the arms and legs to assess the ABI in 43 patients with primary APS (mean (SD) age 40.2 (7.9) years) and 49 healthy subjects (aged 41.0 (11.7)) matched for age and sex. Data on traditional cardiovascular risk factors, such as hypertension, hypercholesterolaemia, presence of diabetes mellitus, nephrotic syndrome or renal failure, smoking, and other variables, were collected at that time for all subjects. A ratio of the highest blood pressure from the posterior tibial or pedal arteries of each leg to the highest blood pressure from the brachial arteries ,1.00 was considered abnormal. Results: Abnormal ABIs were found in 8/43 (19%) patients with primary APS and 2/49 (4%) controls (p = 0.026). No correlation between abnormal ABI and traditional cardiovascular risk factors nor with the presence of aPL was found. Conclusion: Abnormal ABIs are more common in primary APS than in healthy controls, possibly indicating a subclinical atherosclerotic process in these patients.

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“…However, coronary embolism due to this syndrome is not common [11]. Thus antiphospholipid syndrome may cause acute myocardial infarction due to thrombotic occlusion of coronary arteries.…”

Section: Discussionmentioning

confidence: 99%

Acute Thrombotic Occlusion of Right Coronary and Left Circumflex Coronary Arteries in a Patient with Antiphospholipid Syndrome: Successful Stent Implantation

Biceroglu¹,

Demirbas²,

Karaca³

et al. 2010

Case Reports in Medicine

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Antiphospholipid syndrome is a rare disorder. Acute myocardial infarction is uncommon among these patients. Here we report a case of a 44-year-old man with antiphospholipid syndrome admitted for acute inferior myocardial infarction. Performed coronary angiography revealed that both the right coronary and the left circumflex coronary arteries were occluded by thrombi. We successfully performed primary angioplasty and stent implantation for both of the occluded coronary arteries. In the literature, this is the first case with antiphospholipid syndrome in which primary coronary angioplasty with stent implantation was successfully performed for two coronary arteries with acute thrombotic occlusion.

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Primary antiphospholipid syndrome with acute myocardial infarction recanalised by PTCA

Cited by 49 publications

References 12 publications

Acute myocardial infarction in young adults: causes and management

Acute myocardial infarction in young adults: causes and management

Prevalence of an abnormal ankle-brachial index in patients with primary antiphospholipid syndrome: preliminary data

Acute Thrombotic Occlusion of Right Coronary and Left Circumflex Coronary Arteries in a Patient with Antiphospholipid Syndrome: Successful Stent Implantation

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