Hybrid- Life Cycle Assessments (LCA) mostly fails to fully exploit valuable information from Multi-Regional Input-Output (MRIO) models by aggregating regional supply chains to the lower geographical resolution of process LCA databases. We propose a method for sampling the various individual regions within the aggregated regional scope of LCA processes. This sampling not only maximises the information content of the hybrid LCA footprint results by preserving the regional variance, it also allows for using regional price distributions form BACI/UN-COMTRADE international trade statistics to simultaneously improve the accuracy of the hybrid model. In this work we analyse the impact of regional variance and the use of regional price distributions on the uncertainty of the hybrid footprint results for both the carbon (GWP100) and land use footprint and compare this to the variance resulting from price variance only and regional variance only. We find that the median process footprint intensity increases by 7 +18 − 3 % for the GWP100 due to hybridisation, and 90 +143 − 23 % for the Land Use footprint. Our results also show that the magnitude of the footprint uncertainty strongly depends on the product sector of the LCA process and environmental impact considered. Additionally, we illustrate the effect of regional variance and price distributions on a consumption footprint using a case study of Swiss household consumption. Here the truncation error estimates are 8 . 4 +9 . 2 − 2 . 7 % for the GWP100 and 36 +64-14 % for the land use footprint. The relative uncertainties of the truncation error correction are very high (110-178% for the upper limits) moreover the have a strong positive skew. Our results highlight the importance of regionalisation of process LCA databases, as it has the potential to significantly improve both the precision and accuracy of hybrid LCA models.