2010
DOI: 10.1590/s1415-52732010000200009 View full text |Buy / Rent full text
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Abstract: OBJETIVO: Verificar o potencial efeito protetor de suplementação com vitaminas antioxidantes em um modelo de síndrome de isquemia-reperfusão renal em ratos. MÉTODOS: Foram utilizados 29 ratos Wistar, divididos em três grupos: Grupo I e II (n=10 cada), submetidos a indução do estresse oxidativo pela aplicação de 60 minutos de isquemia renal, seguidos de 10 minutos de reperfusão; adicionalmente, os animais do Grupo II foram pré-tratados por doze dias com vitaminas antioxidantes (vitamina C 11,43mg/kg e vitamina … Show more

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“…The present study aimed to evaluate its possible protective effects on renal ischemia. This, in turn, is the genesis of acute renal failure, characterized by elevated levels of urea and creatinine 2 .…”
Section: Discussion Discussion Discussion Discussionmentioning
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“…The present study aimed to evaluate its possible protective effects on renal ischemia. This, in turn, is the genesis of acute renal failure, characterized by elevated levels of urea and creatinine 2 .…”
Section: Discussion Discussion Discussion Discussionmentioning
“…Urea, on its turn, has blood levels changed according to the type of food. Therefore, serum creatinine is more reliable than serum urea 2 , thus characterizing the difference between the normal range and the GPRE group.…”
Section: Discussion Discussion Discussion Discussionmentioning
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“…Several substances have been tested as alternatives to reduce deleterious effects of ischemia/reperfusion syndrome, such as chlorpromazine, verapamil, allopurinol, octreotide, copaiba oil, vitamins (C, D and E) and cyclosporin A. However, the effect of most them was disappointing [1][2][3][4] .…”
Section: ■ Introductionmentioning
“…Todos os trabalhos analisados concordam que diversos alimentos e micronutrientes trazem contributos importantes na prevenção e combate às doenças como a SM 28 , contudo, tais componentes devem estar associados a dietas equilibradas, atividades físicas e alterações no estilo 6,29,30 de vida contemporâneo .…”
Section: Síndrome Metabólica E Questões Nutroterápicasunclassified