Prevalence, pattern, risk factors and outcome of stroke in women: a clinical study of 100 cases from a tertiary care center in South India

Manorenj, Sandhya; Inturi, Snehalatha; Bhargava, Jyotsna; Savya, V. Sai; Areli, Devender; Reddy, Dr. Obul

doi:10.18203/2320-6012.ijrms20161819

Cited by 13 publications

(16 citation statements)

References 8 publications

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“…[18][19][20] Male sex is considered as an important risk factor for stroke. 21,22 Present study also had male preponderance. This may be attributable to a sociocultural bias in India that men are more likely to seek treatment than women, as they may be the soul-earning member of the family.…”

Section: Discussionsupporting

confidence: 53%

“…This may be attributed to higher prevalence of rheumatic heart disease and longer life expectancy in females, findings were similar to previous studies. 15,22 Dilated cardiomyopathy was the most common association with cardio embolism observed in present study. Present findings differed from that reported by GS Naik 15 et al where Ischemic heart disease was the major cardiac risk factor.…”

Section: Discussionmentioning

confidence: 48%

“…Secondly men are habituated to smoking and alcohol use in India than women, when compared to western world where both sexes are equally affected. 22,23 LAA was the most common stroke subtype observed and was at higher rate than that reported from India. 13,15 This may be due to availability of MR angiography's and duplex scan in our center.…”

Section: Discussionmentioning

confidence: 81%

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Trial of ORG 10172 in acute stroke treatment classification and associated risk factors of ischemic stroke: a prospective study from a tertiary care center in South India

2016

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Background: Stroke is the leading cause of acquired disability worldwide. Better understanding of risk factors helps to reduce the community burden of stroke. Aim of the study was to determine pattern of ischemic stroke subtype and associated risk factors. Methods: Of 220 patients with first ever stroke, 168 patients of ischemic stroke were enrolled prospectively from January 2016 to May 2016 at ESIC Superspeciality hospital, Hyderabad. Patients were categorized in accordance with the Trial of Org 10172 in Acute Stroke treatment (TOAST) criteria. Results: Of 168 patients, 110 (65.4%) were males; male to female ratio was 1.8:1. The mean age was years. Small vessel occlusion (SVO) occurred in younger age group as compared to other stroke subtypes. Frequency of large-artery atherosclerosis (LAA) (46.4%) was highest (Extracranial: 41.1%, intracranial: 36.9%), followed by SVO (32.4%), cardio embolism (15.4%), undetermined (4.7%) and other determined causes (1.1%). Risk factors included dyslipidemia (79%), hypertension (67.8%), smoking (58.3%), alcohol use (54.7%), diabetes (40.4%) and physical inactivity (27.3%). Common association observed was smoking (P -0.004) and alcohol (P -0.003) with LAA and SVO, and dilated cardiomyopathy with cardio embolism. Conclusions: LAA was observed frequently than SVO. Frequency of SVO was lower than Asian but higher than western, while cardio embolism was lower than Western and similar to Asian stroke studies. Dyslipidemia was the predominant risk factor than hypertension reported from Asian and Western stroke registry. This unique pattern can be attributed to differences in demographic and risk factor profiles. The study confirms the need for vigorous primary and secondary prevention measures targeting modifiable risk factors of stroke.

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Section: Discussionsupporting

confidence: 53%

Section: Discussionmentioning

confidence: 48%

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Trial of ORG 10172 in acute stroke treatment classification and associated risk factors of ischemic stroke: a prospective study from a tertiary care center in South India

2016

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“…Stroke : It is clinically defined as per WHO criteria, as rapidly developing clinical signs of focal or global disturbance of cerebral function, with symptoms lasting 24 hours or longer or leading to death, with no apparent cause other than vascular origin [7, 16, 19, 20].…”

Section: Methods and Participantsmentioning

confidence: 99%

“…Patients with stroke under the age of 50 years account for 5-10% of all stroke worldwide [6]. It is the leading cause of acquired disability and the third leading cause of death in women worldwide [7].…”

Section: Introductionmentioning

confidence: 99%

Stroke Event Factors among Adult Patients Admitted to Stroke Unit of Jimma University Medical Center: Prospective Observational Study

Fekadu

Wakassa

Tekle

2019

Stroke Research and Treatment

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Background. The fact that the majority of patients come late creates management difficulties as these first hours are important to avoid secondary insults to the brain and preserve the ischemic penumbra. Although thrombolytic treatments are currently not available in our hospital, significant delays during the prehospital or in-hospital phases of care create management difficulties and would make such advanced treatments impossible in the future in Ethiopia. Methods. Prospective observational study was carried at stroke unit of Jimma University Medical Center for 4 consecutive months from March 10 to July 10, 2017. Data was cleaned and entered to Epidata version 3.1 and then exported and analyzed using SPSS version 20.0. Results. A total of 116 eligible stroke patients were recruited during the study period with mean age of 55.1±14.0 years, ranging from 23 to 96 years. The majority of stroke patients were males (62.9%) and from rural areas (72.4%). The median time elapsed between the onset of stroke symptoms and arrival to the hospital was 27 hours. Almost half (47.4%) of the patients presented within 24 hours and 26 (22.4%) patients presented to hospital beyond 72 hours. Majority of patients (40.5%) showed severe neurological deficit on admission and the mean National Institute of health stroke scale (NIHSS) was 15.71 ± 7.52. The mean Glasgow coma scale (GCS) was moderate (12.12±3.35). On hospital arrival systolic blood pressure (SBP) was highly elevated (≥140 mm Hg) in 65.5% of the patients. The circadian pattern showed a significant peak in morning for hemorrhagic stroke (35.7%) and afternoon for ischemic stroke (38.3%). Conclusions. The delay of hospital arrival was a challenge similar to other high income countries for early management of the patients. Studies that attempt to determine some of the factors that impede timely presentation in patients with strokes are advisable to address those issues further.

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30-day and 60-day rates and predictors of mortality among adult stroke patients: Prospective cohort study

Fekadu

Chelkeba

Melaku

et al. 2020

Annals of Medicine and Surgery

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Prevalence, pattern, risk factors and outcome of stroke in women: a clinical study of 100 cases from a tertiary care center in South India

Cited by 13 publications

References 8 publications

Trial of ORG 10172 in acute stroke treatment classification and associated risk factors of ischemic stroke: a prospective study from a tertiary care center in South India

Trial of ORG 10172 in acute stroke treatment classification and associated risk factors of ischemic stroke: a prospective study from a tertiary care center in South India

Stroke Event Factors among Adult Patients Admitted to Stroke Unit of Jimma University Medical Center: Prospective Observational Study

30-day and 60-day rates and predictors of mortality among adult stroke patients: Prospective cohort study

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