Prevalence of the presystolic wave in echocardiography and its association with the extent of coronary artery disease in patients with chronic stable angina

Abstract

Introduction Since mortality and morbidity of coronary artery disease are high, there is a need for non‐invasive diagnostic methods for early diagnosis and prediction of ischemic heart disease (IHD) outcome. This study aimed to assess the relationship between angiographic findings, the Presystolic wave (PSW) and some of the ischemic related parameters in echocardiography of the patients with chronic stable angina. Materials and methods This cross‐sectional study was conducted on the patients with chronic angina pectoris who referred to a tertiary hospital for coronary angiography in Mashhad, Iran. Demographic and medical history of the patients, as well as echocardiography findings, including ejection fraction (EF), regional wall motion abnormalities (RWMA), PSW and diastolic function were recorded. Angiographic findings, including SYNTAX score were also assessed. Results A total of 220 patients (132 males and 88 females) with the mean age of 62.43 ± 11.40 years old participated in this study. The prevalence of PSW was 49.1%. The absence of the PSW was related to more RWMA (P =.002), and higher stages of left ventricular diastolic dysfunction (LVDD) (P =.029) and higher SYNTAX score (P =.001). There was a significant association between the absence of the PSW and EF categories, especially in severe LV systolic dysfunction (LVEF < 30%) (P =.001). Conclusions The findings of this study revealed that PSW is strongly associated with the SYNTAX score. The absence of the PSW may indicate patients at high‐risk clinical status (higher SYNTAX score, severe systolic dysfunction, more RWMA, and higher stages of LVDD).

The relationship of left ventricular outflow tract presystolic wave and 24-h ambulatory blood pressure measurements

“…Our study differs from their study by the means of the studied subgroup, which is the overall systemic hypertension. The presystolic wave was associated with a higher ejection fraction (EF) after myocardial infarction (MI) [3,17]. Higher myocardial performance index, left ventricular hypertrophy (LVH), age and mitral inflow A wave have also been associated with presystolic wave [18].…”

The impact of radioactive iodine treatment on subclinical left ventricular dysfunction in patients treated for differentiated thyroid cancer: assessing the predictive value of presystolic wave

“…There are also studies investigating potential relationships between coronary artery disease and the lack of presystolic waves. The absence of presystolic wave was found to be predictive for extensive coronary artery disease and higher Syntax score [18,19]. Another study conducted by Saylik et al [20] revealed that presystolic wave was a common occurrence among subjects with subclinical hypothyroidism and that presystolic waves were independently associated with subclinical LV dysfunction in subjects with subclinical hypothyroidism.…”