Prevalence of metabolically healthy obese phenotype and associated factors in South American overweight adolescents: A cross-sectional study

Remor, Jane Maria; Lopes, Wendell Arthur; Locateli, João Carlos; Oliveira, Ronano Pereira; Simões, Caroline Ferraz; Barrero, Carlos Andres Lopera; Nardo, Nélson

doi:10.1016/j.nut.2018.08.017

Cited by 12 publications

(12 citation statements)

References 45 publications

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“…This study shows that the obesity rate of male students is higher than that of female students, and the risk of being overweight is 1.93 times higher than that of female students. This result is similar to the research of many scholars at home and abroad ( 20 – 23 ), which means that in the current school health promotion plan in China, personalized promotion strategies should be developed for high-risk cases or gender differences. This study also found that when the parents' education level is reduced by one level, the risk of overweight of their children will be increased to 1.859 times of the original.…”

Section: Discussionsupporting

confidence: 83%

A Study on the Relationship Between Adolescent Health Behavior, BMI, and Blood Physical and Chemical Properties

Peng

Yin

Wang

et al. 2022

Front. Public Health

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In this study, the blood test index, demographic data, and health promotion behavior of adolescents were analyzed to provide a reference for early prevention and treatment of physical decline and abnormal biochemical indexes of adolescents. Using a cross-sectional study design, 1,436 valid samples were obtained by stratified random sampling, and the data were processed by SPSS21.0 statistical analysis software. The results showed that the overall health-promoting lifestyle of adolescents was good, and the interpersonal support behavior was the best, and the health responsibility and sports participation behavior were the worst; the interpersonal support and sports participation behavior of adolescents with normal weight were significantly better than those with overweight or light weight, while the overall health-promoting behavior of adolescents with high fasting blood glucose (FBG) before meals was poor, those with high glutamate pyruvate transaminase (GPT) had poor nutritional behavior and health responsibility behavior, while those with high uric acid (UA) had poor interpersonal support and stress coping behavior. The overweight rate and abnormal detection rate of UA and triglyceride (TG) in boys were significantly higher than those in girls, and the higher BMI of teenagers, the higher abnormal detection rate of GPT, UA, and TG, the better nutritional behavior, health responsibility behavior, and sports participation behavior, the lower abnormal detection rate of GPT, UA, and TG; the higher education level of parents, the better teenagers' sports participation and health responsibility behavior, the lower the incidence of overweight, the more time they spend playing online games and drinking sugary drinks on weekdays (or holidays), the higher the incidence of overweight.

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Section: Discussionsupporting

confidence: 83%

A Study on the Relationship Between Adolescent Health Behavior, BMI, and Blood Physical and Chemical Properties

Peng

Yin

Wang

et al. 2022

Front. Public Health

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“…Finally, the following 103 articles were selected: [ 24 – 34 , 44 – 135 ] after the evaluation of the full texts, 78 were excluded for the following reasons: (1) the design of the studies did not meet the inclusion criteria defined for this review [ 44 – 46 , 48 – 53 , 55 – 57 , 59 – 61 , 65 , 66 , 68 – 73 , 79 , 81 , 84 , 86 , 88 – 91 , 97 , 100 – 104 , 106 , 108 , 110 , 112 – 117 , 119 – 122 , 124 – 132 , 134 , 135 ] (2) the studies did not present an evaluation of whole body FFM/LBM, these were [ 47 , 54 , 58 , 62 – 64 , 67 , 74 – 78 , 80 , 82 , 83 , 85 , 92 – 96 , 105 , 107 , 109 , 111 , 123 ] and (3) another language [ 87 ] (Fig. 1 ).…”

Section: Resultsmentioning

confidence: 99%

Fat-free/lean body mass in children with insulin resistance or metabolic syndrome: a systematic review and meta-analysis

et al. 2022

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Background Lean / Fat Free Body Mass (LBM) is metabolically involved in active processes such as resting energy expenditure, glucose uptake, and myokine secretion. Nonetheless, its association with insulin sensitivity / resistance / glucose tolerance and metabolic syndrome remains unclear in childhood. Methods The current investigation aimed to examine the differences in fat-free mass /lean body mass according to the presence of insulin sensitivity/insulin resistance/glucose tolerance/metabolic syndrome in children. A systematic search was carried out in Medline/PubMed, Embase, Scopus, Web of Science, and SciELO, covering the period from each database’s respective start to 21 June 2021. Two researchers evaluated 7111 studies according to the inclusion criteria: original human studies, written in English or Spanish, evaluating fat-free mass/lean body mass in children and adolescents including both with and without insulin sensitivity/insulin resistance /glucose tolerance and metabolic syndrome and reported the differences between them in terms of fat free mass/lean body mass. The results of the studies were combined with insulin sensitivity, insulin, resistance, glucose tolerance and metabolic syndrome. The standardized mean difference (SMD) in each study was calculated and combined using the random-effects model. Heterogeneity between studies was tested using the index of heterogeneity (I2), leave-one-out sensitivity analyses were performed, and publication bias was assessed using the Egger and Begg tests. Results Finally, 15 studies which compared groups defined according to different glucose homeostasis criteria or metabolic syndrome out of 103 eligible studies were included in this systematic review and 12 studies in the meta-analysis. Meta-analysis showed lower fat-free mass/lean body mass percentage in participants with insulin resistance/glucose tolerance/metabolic syndrome (SMD -0.47; 95% CI, − 0.62 to − 0.32) while in mass units (kg), higher values were found in the same group (SMD, 1.01; 95% CI, 0.43 to 1.60). Conclusions Our results identified lower values of fat-free mass/lean body mass (%) in children and adolescents with insulin resistance/glucose tolerance/metabolic syndrome and higher values of fat-free mass/lean body mass when these are expressed in kg. The evidence of the impact of lean mass on children’s glucose homeostasis or metabolic syndrome is limited, so future studies research should focus on explaining the effect of fat-free mass/lean body mass on different metabolic outcomes. Moreover, it may be interesting to evaluate the quality (muscle density) or functional (muscle strength) outcomes in addition to both absolute (kg) and relative (%) values in future studies. The systematic review was prospectively registered at PROSPERO (registration number CRD42019124734; available at: http://www.crd.york.ac.uk/prospero [accessed: 05 April 2019]).

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“…В последнее время отсутствие стандартного подхода к использованию одних и тех же наборов критериев и предельных значений для определения метаболических нарушений является основным источником высокой вариабельности в распространенности МÇФО ожирения, о которой сообщалось ранее [3].…”

Section: Discussionunclassified

“…Приблизительно 10-30% людей с ожирением метаболически здоровы, несмотря на чрезмерное накопление жира в организме. Это явление упоминается в современной литературе как метаболически здоровый фенотип ожирения (MÇФО) [3]. Тем не менее основным препятствием на пути понимания ýпидемиологии МÇФО и его долгосрочной перспективы является противоречивое определение в различных исследованиях [4][5][6].…”

Section: Introductionunclassified

Gender and age related features of metabolically healthy obesity phenotype prevalence

et al. 2020

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Половозрастные особенности распространенности метаболически здорового фенотипа ожирения Мустафина С.В., Винтер Д.А., Щербакова Л.В., Малютина С.К., Рагино Ю.И., Рымар О.Д. Научно-исследовательский институт терапии и профилактической медицины (НИИТПМ)филиал Федерального исследовательского центра «Институт цитологии и генетики» Сибирского отделения Российской академии наук (ФИЦ ИЦиГ СО РАН) Россия, 630089, г. Новосибирск, ул. Бориса Богаткова, 175/1 РЕЗЮМЕ Цель. Изучить половозрастные особенности метаболически здорового фенотипа ожирения (МÇФО).Материалы и методы. Использованы материалы кросс-секционного исследования популяционной когорты (проект HAPIEE, г. Новосибирск) (n = 3 197 человек, среди них 857 (26,8%) мужчин и 2 340 (73,2%) женщин, с индексом массы тела (ИМТ) ≥30 кг/м²). МÇФО определен в соответствии с различными классификациями: 1) IDF (2005) -окружность талии (ОТ) ≥94 см у мужчин и ≥80 см у женщин и любой компонент метаболического синдрома (МС) по IDF или без него; 2) NCEP ATP III (2001) при наличии 2 и (или) менее компонентов МС; 3) критерии РКО (2017) -индекс окружность талии / окружность бедер (ОТ / ОБ) ≤0,9 у мужчин и ОТ / ОБ ≤ 0,85 у женщин.Результаты. Среди лиц с ожирением частота МÇФО по критериям IDF -23,2%; NCEP ATP III -41,8%; РКО -27,1%. Частота МÇФО выше у женщин, чем у мужчин, и она значимо снижается с возрастом в женской популяции. Для лиц с МÇФО по всем классификациям характерно повышенное среднее значение артериального давления при нормальных средних значениях уровня триглицеридов и холестерина липопротеидов высокой плотности. Обследованные с МÇФО по критериям РКО демонстрируют более высокие показатели частоты всех изучаемых кардиометаболических факторов риска, чем при использовании других критериев МÇФО.Выводы. Частота МÇФО варьирует в зависимости от используемой классификации. У женщин частота МÇФО достоверно выше, чем у мужчин. С возрастом отмечается значимое снижение частоты МÇФО у женщин. Частота артериальной гипертонии, абдоминального ожирения, уровень глюкозы крови натощак, холестерина липопротеидов низкой плотности и гипертриглицеридемия выше у лиц с наличием МÇФО по критериям РКО.Ключевые слова: ожирение, распространенность, половые различия, метаболически здоровый фенотип ожирения.Конфликт интересов. Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с публикацией настоящей статьи.

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Prevalence of metabolically healthy obese phenotype and associated factors in South American overweight adolescents: A cross-sectional study

Cited by 12 publications

References 45 publications

A Study on the Relationship Between Adolescent Health Behavior, BMI, and Blood Physical and Chemical Properties

A Study on the Relationship Between Adolescent Health Behavior, BMI, and Blood Physical and Chemical Properties

Fat-free/lean body mass in children with insulin resistance or metabolic syndrome: a systematic review and meta-analysis

Gender and age related features of metabolically healthy obesity phenotype prevalence

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