Prevalence of major and minor electrocardiographic abnormalities and their relationship with cardiovascular risk factors in Angolans

Gonçalves, Mauer; Pedro, João Mário; Silva, Carina; Magalhães, Pedro; Brito, Miguel

doi:10.1016/j.ijcha.2022.100965

Cited by 6 publications

(7 citation statements)

References 46 publications

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“…This result is higher than the studies from Spain (3.5%), 36 China (1.28%), 35 and Angola (0.71%). 15 This may be because half of the study participants in the current study were epileptic patients which may raise the proportion of Q wave abnormality. This study revealed that 3.8% of study participants had left ventricular hypertrophy.…”

Section: Discussionmentioning

confidence: 91%

“…This finding was supported by a study in Angola. 15 The harmful components of cigarette smoke like nicotine may be responsible for this difference. Nicotine is capable of altering the normal function of inward and delayed rectifier potassium channels, channels important for excitability and maintenance of membrane potential stability.…”

Section: Discussionmentioning

confidence: 99%

“…Electrocardiographic abnormalities in people with epilepsy are caused by depolarization and repolarization defects due to disruption of ion channels by anti-epileptic drugs (AEDs), myocardial ischemia due to prolonged contraction in repeated autonomic stimulation of the heart, and as a result of genetic mutation of ion channels found both in the brain and the heart. 12 , 13 These electrocardiographic changes are associated with age, 14 gender, 14 alcohol, cigarette smoking, 15 chat chewing, 16 overweight and/or obesity, 17 hypertension, 9 antiepileptic drugs (AEDs), 18 duration of epilepsy, 19 and frequency of seizure. 20 …”

Section: Introductionmentioning

confidence: 99%

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Electrocardiogram Abnormalities and Associated Factors Among People with and without Epilepsy Attending the Outpatient Department at Referral Hospitals in Amhara Regional State, Northern Ethiopia, 2022: Institutional-Based Comparative Cross-Sectional Study

Adane,

Melese,

Tesfaye

et al. 2023

NDT

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Background Epilepsy is a brain disease that is associated with electrocardiographic (ECG) abnormalities. However, this evidence is limited in Ethiopia. Studying ECG abnormality in epileptic patients could help minimize the cardiac problems and death of epileptic patients by early screening. This study was aimed to assess electrocardiogram abnormalities and associated factors among people with and without epilepsy at referral hospitals in Amhara Regional State (ARS), northern Ethiopia, 2022. Methods Institutional-based comparative cross-sectional study was conducted from April 20 to June 20, 2022. Three referral hospitals in ARS were selected by simple random sampling. Epileptic patients were selected by systematic random sampling, and 403 age- and sex-matched participants were selected from attendants of patients in the outpatient department. Interviewer-administered questionnaire and digital electrocardiograph were used for data collection. Data were entered to EpiData version 4.6 and exported to stata version 14 for analysis. Variables with P value <0.25 in bivariable analysis were entered to multivariable binary logistic regression. Strength of association was determined by adjusted odds ratio with a 95% confidence interval (CI). Results The prevalence of ECG abnormality was 40.0% (95% CI = 34.7–46.8) and 29.0% (95% CI = 23.2–34.3) in epileptic and non-epileptic subjects, respectively. The odds of ECG abnormality was 58% higher among epileptic patients. Divorce, duration of epilepsy, uncontrolled epilepsy, former/current smoker, adequate physical activity, hypertension, and overweight/obesity were associated with ECG abnormality among epileptic patients. Conclusion and Recommendations The proportion of ECG abnormality was higher among the epileptic than the non-epileptic group. This should be a wake-up call for stakeholders to establish appropriate measurements to reduce cardiac issues of epileptic patients.

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Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Electrocardiogram Abnormalities and Associated Factors Among People with and without Epilepsy Attending the Outpatient Department at Referral Hospitals in Amhara Regional State, Northern Ethiopia, 2022: Institutional-Based Comparative Cross-Sectional Study

Adane,

Melese,

Tesfaye

et al. 2023

NDT

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“…In total, by utilizing the MC criteria, major ECG abnormalities were observed in 2.9% of study population and found to be more common among men compared to women. Several other studies have reported comparatively higher prevalence of major abnormalities among men (4,22,27,28), while few have stated the opposite (29). Moreover, De Bacquer et al measured a significant sex ratio (M to F) of 1.66 in their study sample (4).…”

Section: Major Abnormalitiesmentioning

confidence: 85%

Age and gender differences of electrocardiographic basic values and abnormalities in general adult population; Tehran Cohort Study

Afzalian¹,

Ahmadi²,

Jalali³

et al. 2022

Preprint

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Introduction Although several studies are available regarding baseline Electrocardiographic (ECG) parameters, major and minor ECG abnormalities, there is a big controversy regarding their age and gender differences in literature, thus we aimed to investigate any possible age or gender ECG discrepancies in general adult population. Methods Data of 7630 adults aged ≥35 years from Tehran Cohort Study who were registered between March 2016 to March 2019 were collected. ECG basic values, major, and minor ECG abnormalities-defined according to the Minnesota Code-were analyzed and compared between genders, and four distinct age groups. Odds ratio of having any major ECG abnormality between males, and females stratiﬁed by age, and number of cardiovascular risk factors was calculated. Results ECG information of 7630 participants was available. The average age was 53.6 (±12.66), and women made up 54.2% (n=4132) of subjects. The average heart rate (HR) was higher among women(p<0.0001), while the average values of QRS duration, P wave duration, and RR intervals were higher among men(p<0.0001). Major ECG abnormalities were observed in 2.9% of study population (with right bundle branch block, left bundle branch block, and Atrial Fibrillation being the most common) and were more prevalent among men compared to women (3.1% vs 2.7% p=0.188). Moreover, minor abnormalities were observed in 25.9% of study population, and again were more prevalent among men (36.4% vs 17% p<0.001). Prevalence of major ECG abnormalities was significantly higher in participants older than 65 years old, and participants who had ≥3 conventional cardiovascular (CV) risk factors. Conclusion Basic ECG values is different in male and female general population. In addition, major and minor ECG abnormalities were roughly more prevalent in male subjects. In both genders, odds of having major ECG abnormalities surges with increase in number of conventional CV risk factors and age.

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“…The MC classified the electrocardiograms as presenting major, minor alterations or absence of abnormalities. The Normal limits of the ECG, as well as ECG abnormalities in this population were published elsewhere (Gonçalves et al, 2020(Gonçalves et al, , 2021(Gonçalves et al, , 2022. In view of the presence of alterations, abnormal ECGs were manually reviewed by two cardiologists, in order to guarantee the quality of the coding.…”

Section: Electrocardiographic Recordingmentioning

confidence: 99%

Electrocardiographic findings in pregnant women in Angola

Gonçalves

Pedro

Silva

et al. 2022

Noninvasive Electrocardiol

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Prevalence of major and minor electrocardiographic abnormalities and their relationship with cardiovascular risk factors in Angolans

Cited by 6 publications

References 46 publications

Electrocardiogram Abnormalities and Associated Factors Among People with and without Epilepsy Attending the Outpatient Department at Referral Hospitals in Amhara Regional State, Northern Ethiopia, 2022: Institutional-Based Comparative Cross-Sectional Study

Electrocardiogram Abnormalities and Associated Factors Among People with and without Epilepsy Attending the Outpatient Department at Referral Hospitals in Amhara Regional State, Northern Ethiopia, 2022: Institutional-Based Comparative Cross-Sectional Study

Age and gender differences of electrocardiographic basic values and abnormalities in general adult population; Tehran Cohort Study

Electrocardiographic findings in pregnant women in Angola

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