Prevalence of &lt;i&gt;Helicobacter pylori&lt;/i&gt; among Nigerian patients with dyspepsia in Ibadan

Jemilohun, Abiodun Christopher; Otegbayo, Jesse Abiodun; Ola, S O; Oluwasola, Olayiwola; Akere, Adegboyega

doi:10.4314/pamj.v6i1.69090

Cited by 59 publications

(54 citation statements)

References 6 publications

(14 reference statements)

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“…This is in concordance with the observation of Jemilohun. et al [17] This may be due to low number of cases being evaluated in our study. H. pylori have been found in 90% of patient with chronic gastritis, 95 % with duodenal ulcer, 70% with gastric ulcer and 50% with gastric cancer.…”

Section: Discussionmentioning

confidence: 48%

Prevalence of Helicobacter Pylori among Patients undergoing Gastrodudenoscopy in a Hospital in Western Nepal

Shakya¹,

Regmi²,

Adhikari³

2017

J Lumbini Med Coll

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Introduction: Helicobacter pylori (H. pylori) related chronic gastritis is a major health problem worldwide, specially in the developing countries. The prevalence of H. pylori infection has been reported to vary between and even within countries. There are limited data on this infection in Western Nepal. Our objective was to study the prevalence of H. pylori infection and its association with presenting complains and upper gastrointestinal diseases. Methods: Medical records of patients undergoing gastrodudenoscopy and biopsy for various upper gastrointestinal symptoms from 1st of January 2015 to 30th of June 2017 were reviewed for presence of H. pylori infection, demographics, indications for gastrodudenoscopy, and histopathology findings. T-test, Chi-square test, and Fisher exact test were applied. Results: Two hundred fifty six patients (135 male and 121 female) with a mean age of 47 (SD = 16.5) underwent gastroscopic biopsy and had an overall H. pylori prevalence of 24.6%. H. pylori infection was most commonly noted between 41 to 60 years of age. Gender did not seem to be significantly associated (p = 0.82) but gastrointestinal bleed was significantly associated with H. pylori infection (p = 0.006). The most common histopathological diagnosis was gastritis followed by gastrodudenitis; however, none of the diagnosis were found to be significantly associated with H. pylori infection. Conclusion: The overall prevalence of H. pylori infection was 24.6% and was most common between 40 to 60 years of age. Heart burn was the most common symptom and gastrointestinal bleed was the only significantly associated symptom with H. pylori infection.

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Section: Discussionmentioning

confidence: 48%

Prevalence of Helicobacter Pylori among Patients undergoing Gastrodudenoscopy in a Hospital in Western Nepal

Shakya¹,

Regmi²,

Adhikari³

2017

J Lumbini Med Coll

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“…Although interval usage of NSAID is not unlikely among our patients, we did not find any patient with NSAID‐induced dyspepsia during this period. An alternative explanation could be the high prevalence of Helicobacter pylori infection in southwestern Nigerian community although it does not appear that PWE have higher frequency of H. pylori infection when compared .…”

Section: Discussionmentioning

confidence: 96%

Impact of somatic comorbidities on quality of life of patients living with epilepsy in Sagamu, Nigeria

et al. 2014

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“…20,21 In a similar study on the prevalence of H. pylori test done in Ibadan, Nigeria among 86 patients using rapid urease test, the most common finding was gastritis. 22 However in another study in Ilorin, Nigeria among 125 patients with dyspepsia, 93.5% were positive on serology while 80.0% was found on histology. 23 H. Pylori infection of the gastric mucosa causes an active chronic gastritis, which in some cases progresses to multifocal atrophic gastritis.…”

Section: Discussionmentioning

confidence: 99%

Changing patterns of the prevalence of <i>Helicobacter pylori</i> among patients at a corporate hospital in Ghana

Darko¹,

Yawson²,

Osei³

et al. 2015

Ghana Medical Journal

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SUMMARY Introduction:Helicobacter pylori (H. pylori) discovered in 1982, has strongly been associated with multiple clinical disorders of the gastrointestinal tract. This study described the prevalence of H. pylori among large numbers of patients over two different time periods in Accra, Ghana. Methods: It was a retrospective records review on patients attending a quasi-government hospital in Accra, Ghana, during two time periods, 1999 and 2012. A total of 2401 records were reviewed, 1128 in first period and 1273 in second period. Biopsy was taken from the gastric antrum for Rapid Urease Test (RUT) in identifying H. Pylori. Data on patient characteristics, clinical diagnosis and findings upon endoscopy were analyzed by simple descriptive statistics. Associations between categorical outcome variables were determined by Chi square test at 95% significance level. Results: H. pylori infection was high in patients with upper gastrointestinal symptoms 69.7% (1999) and 45.2% (2012), and was even higher in patients with gastritis and duodenal ulcer. H. pylori infection however, decreased among patients over the period, 69.7% in 1999 to 45.2% in 2012. Sex differences in H. pylori infection was identified (higher among males) and young adults (21-40 years). Commonest symptom in all patients was non-ulcer dyspepsia, 86.9% in 1999 and 84.2% in 2012, while gastritis and duodenal ulcer were the commonest endoscopic finding in the two periods. Conclusion: Appropriate management guidelines in West Africa considering the high background H. pylori infection and other co-infections requiring particular antibiotic combination therapy is required.

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Prevalence of <i>Helicobacter pylori</i> among Nigerian patients with dyspepsia in Ibadan

Abstract: Introduction: Determination of the true prevalence of Helicobacter pylori (H. pylori) is difficult in a hyper-endemic area like Nigeria with use of

Cited by 59 publications

References 6 publications

Prevalence of Helicobacter Pylori among Patients undergoing Gastrodudenoscopy in a Hospital in Western Nepal

Prevalence of Helicobacter Pylori among Patients undergoing Gastrodudenoscopy in a Hospital in Western Nepal

Impact of somatic comorbidities on quality of life of patients living with epilepsy in Sagamu, Nigeria

Changing patterns of the prevalence of <i>Helicobacter pylori</i> among patients at a corporate hospital in Ghana

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