Prevalence of hypodontia and associated factors: a systematic review and meta-analysis

Khalaf, Khaled; Miskelly, John; Voge, Elena; Macfarlane, Tatiana V.

doi:10.1179/1465313314y.0000000116

Cited by 205 publications

(297 citation statements)

References 63 publications

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“…Mandibular second premolars are the most commonly affected and account for 29.9% of all congenitally missing teeth, followed by maxillary lateral incisors (24.3%). Maxillary canines on the other hand made up only 2.5% of all congenitally missing teeth [3]. Our case series showed three siblings with variable expressions of hypodontia.…”

Section: Discussionmentioning

confidence: 88%

“…Different continents displayed different prevalence values with Africa being the highest at 13.4%, followed by Europe at 7%, Asia and Australia both 6.3%, North America 5% and Latin America and the Caribbean displaying the lowest prevalence values at 4.4%. Most individuals had only one or two teeth missing [3]. Mandibular second premolars are the most commonly affected and account for 29.9% of all congenitally missing teeth, followed by maxillary lateral incisors (24.3%).…”

Section: Discussionmentioning

confidence: 99%

“…Hypodontia can be inherited as an isolated trait or is usually associated with several syndromes such as ectodermal dysplasia, Down Syndrome and cleft lip and palate [2,3]. Non-syndromic hypodontia is more common, with varying numbers of teeth that can be involved; however, the incisor-premolar type predominates [3]. Various studies report that hypodontia is more commonly seen in the maxillary arch and the permanent dentition is much more affected than the primary dentition [3,4].…”

Section: Introductionmentioning

confidence: 99%

“…Non-syndromic hypodontia is more common, with varying numbers of teeth that can be involved; however, the incisor-premolar type predominates [3]. Various studies report that hypodontia is more commonly seen in the maxillary arch and the permanent dentition is much more affected than the primary dentition [3,4]. A review of the literature indicates that the etiology of hypodontia is multifactorial and has been reported to be due to genetic as well as environmental factors [5].…”

Section: Introductionmentioning

confidence: 99%

“…Oligodontia is a severe and rare form of tooth agenesis which is defined as the absence of six or more teeth, while the congenital absence of less than six teeth is referred to as hypodontia. Hypodontia can be inherited as an isolated trait or is usually associated with several syndromes such as ectodermal dysplasia, Down Syndrome and cleft lip and palate [2,3]. Non-syndromic hypodontia is more common, with varying numbers of teeth that can be involved; however, the incisor-premolar type predominates [3].…”

Section: Introductionmentioning

confidence: 99%

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Non Syndromic Familial Hypodontia - A Case Series

Binladen¹,

Mahmoud²,

Chandwani³

et al. 2018

EDUJ

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Aim:The aim of this case report is to discuss the features of non-syndromic familial hypodontia, which was noted in three siblings who had an unremarkable medical history. Summary: Congenital absence of teeth is a common dental anomaly referring to teeth that fail to erupt in the oral cavity and remain invisible in radiographs. Congenital tooth agenesis is defined by the number of missing teeth, excluding the third molars; hypodontia refers to the absence of less than six teeth, while oligodontia is the absence of six or more teeth. Tooth agenesis can occur as part of a genetic syndrome such as the cleft lip and palate, ectodermal dysplasia and Trisomy 21 (syndromic hypodontia) or an isolated trait (nonsyndromic hypodontia). Non-syndromic hypodontia is the most common form and can be familial or sporadic. The most supported etiological theory suggests that tooth agenesis may be due to a combination of genetic and environmental factors, which lead to disturbances in the tooth germ during the initial formation stages. This case series reports bilateral agenesis of the maxillary canines in siblings, which is quite rare in occurrence. The management of these anomalies involves a multidisciplinary approach in order to restore esthetics and function. An early diagnosis can lead to effective treatment planning and satisfactory results. Key learning points:The clinical manifestations as well as the short and long term management of this condition are discussed.

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Section: Discussionmentioning

confidence: 88%

Section: Discussionmentioning

confidence: 99%