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citations
Cited by 18 publications
(16 citation statements)
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References 13 publications
(16 reference statements)
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“…Exact logistic regression analysis adjusting for age revealed a trend towards increased prevalence of Asian-American variants in HIV-positive women compared with HIV-negative women (exact p ϭ 0.097) and significantly higher prevalence of variants with a mutation at nt 350 in HIV-positive women (exact p ϭ 0.026) This is the first study in Brazil to evaluate HPV16 variants among HIV-negative and -positive women. In this series, although we did not observe an increased oncogenic potential for the Asian-American variants of HPV16, other studies (2,9,30); conducted in the Americas showed conflicting results. Berumen et al (2) reported that HPV16 Asian-American variants are able to confer a higher risk for cervical cancer than HPV16 European variants and also that almost a quarter of all cervical cancers in Mexico can be attributed to Asian-American variants.…”
Section: Gheit Et Alcontrasting
confidence: 85%
“…However, these findings have not been confirmed in other studies (4,14). In Brazil, the predominant variants are European, followed by AsianAmerican with Q14H, H78Y, and L83V simultaneous mutations (9,30). Interestingly, regional differences in the prevalence of HPV16 variants may also be associated with host immune responses (12).…”
Section: Introductionmentioning
confidence: 83%
“…This was also found in southeastern (Villa et al, 2000) and central Brazil (Cruz et al, 2004;Alencar et al, 2007). Variants of HPV type 16 are typically classified into European, African, Asian-American, and North-American, or Amerindian (Yamada et al, 1997).…”
Section: Prevalence Of the Types Of Hpvmentioning
confidence: 88%
“…Cervical cancer is the most common disease in Brazilian women, and infection by HPV is the main risk factor for development of this pathology. In Brazil, most studies of HPV were conducted in southeastern (Villa et al, 2000) or in central regions of the country (Cruz et al, 2004;Alencar et al, 2007;Cerqueira et al, 2008).…”
Section: Introductionmentioning
confidence: 99%
“…HPV-16 and -18 are associated with nearly 70% of cervical carcinomas worldwide, with HPV-18 being identified in approximately 20% of the high-risk infections [1]. The nucleotide variability of HPV-16 and -18 has been extensively studied, and several molecular variants have been described on the basis of their geographical distribution [2][3][4][5]. HPV-18 variants co-evolved with the three major phylogenetic human branches: Africans, Caucasians, and Asians, and were clustered into three distinct groups; European (E), Asian-American (AA), and African (Af) [6].…”
Section: Introductionmentioning
confidence: 99%