2015
DOI: 10.1590/s0102-67202015000200007
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Prevalence of gallstones in 1,229 patients submitted to surgical laparoscopic treatment of GERD and esophageal achalasia: associated cholecystectomy was a safe procedure

Abstract: BackgroundAssociation between esophageal achalasia/ gastroesophageal reflux disease (GERD) and cholelithiasis is not clear. Epidemiological data are controversial due to different methodologies applied, the regional differences and the number of patients involved. Results of concomitant cholecistectomy associated to surgical treatment of both diseases regarding safety is poorly understood.AimTo analyze the prevalence of cholelithiasis in patients with esophageal achalasia and gastroesophageal reflux submitted … Show more

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Cited by 6 publications
(7 citation statements)
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References 20 publications
(19 reference statements)
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“…According to Giraldo et al 26 , women exhibit a greater immune response, both cell-mediated and humoral, are more resistant to infections, and are more susceptible to autoimmune diseases, probably due to the action of female sex hormones. Trastulli et al 31 reported that uncontrolled hyperinflammatory responses caused by surgical trauma can lead to systemic immunosuppression, increasing postoperative morbidity and mortality.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…According to Giraldo et al 26 , women exhibit a greater immune response, both cell-mediated and humoral, are more resistant to infections, and are more susceptible to autoimmune diseases, probably due to the action of female sex hormones. Trastulli et al 31 reported that uncontrolled hyperinflammatory responses caused by surgical trauma can lead to systemic immunosuppression, increasing postoperative morbidity and mortality.…”
Section: Discussionmentioning
confidence: 99%
“…Laparoscopic cholecystectomy has become the gold standard for surgical treatment of benign gallbladder disease. The advantages of this procedure compared to laparotomy include smaller incisions, reduced surgical trauma, less postoperative pain, faster recovery times, a shorter hospital stay, and faster return to normal activities and work 1 , 7 , 25 , 26 . The use of a single umbilical incision for gallbladder removal was an interesting innovation and single-incision laparoscopic cholecystectomy has gained momentum in the literature since its description by Navarra et al 21 .…”
Section: Introductionmentioning
confidence: 99%
“…Among the 446 individuals studied, 26% (116) died naturally. In this group, 56% (65) were male, 71% (82) were non-white, and 20% 23 used alcohol. This population was thin (mean BMI 24.29±5.42) and older than the people in the violent death group (65 men, average age ± standard deviation 53.86±17.52 years, and 51 women, average age 54.27±18.6 years).…”
Section: Resultsmentioning
confidence: 95%
“…In Brazil, studies of autopsy results in people over 20 years of age have reported a prevalence of cholelithiasis of 9.07% in Triângulo Mineiro/MG 7 , 11.7% in Campinas/SP 21 and 19.3% in São Paulo/SP 8 , whereas studies using ultrasound found values of 9.3% in Curitiba/PR 12 and 18.4% in the state of Maranhão 22 . The most recent data from Brazil reported a prevalence of cholelithiasis of 11.43% based on ultrasound evaluations, although the study included patients with GERD (gastroesophageal reflux disease) and esophageal achalasia 23 . Regarding other countries in the Americas, studies of autopsy results found a prevalence of cholelithiasis of 9.1% in Chicago, USA 2 ; 14.3% in Mexico 3 ; and 26.6% in Santiago, Chile 4 , whereas studies using ultrasonography found values of 28.5% in Chile 11 and 20.5% 10 and 21.9% 24 in Argentina and, in the USA, the prevalence was 5.3% and 13.9% in non-Hispanic black men and women, respectively, the ethnic group with the lowest prevalence 1 .…”
Section: Discussionmentioning
confidence: 99%
“…Regarding enteral nutrition, gastrostomy and fundoplication did not significantly correlate between the groups. However, vagal nerve damage due to fundoplication is involved in gallstone formation (Stahlgren et al 1980;Sallum et al 2015), and further investigation is warranted. No significant association was found between constipation and its management in the present study.…”
Section: Discussionmentioning
confidence: 99%