Prevalence of Chronic Kidney Disease in Hypertensive Patients in Ghana

Osafo, Charlotte; Mate-Kole, Michael; Affram, K; Adu, Dwomoa

doi:10.3109/0886022x.2011.565140

Cited by 58 publications

(82 citation statements)

References 26 publications

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“…Risk markers associated with presence of albuminuria in Caucasians and Asians with hypertension include age, diabetes mellitus (DM), obesity, smoking, and insufficient blood pressure (BP) control . Knowledge on risk markers suggesting presence of albuminuria among patients with hypertension in sub‐Saharan Africa (SSA) has only been investigated in urban areas and is, in general, comparable with those of the Western world . The lifestyle and living conditions in rural areas of SSA differ from urban environments in terms of physical activity, nutrition, and patterns of cardiovascular disease .…”

mentioning

confidence: 99%

Several Conventional Risk Markers Suggesting Presence of Albuminuria Are Weak Among Rural Africans With Hypertension

Rasmussen

Nordin

Thomsen

et al. 2015

J of Clinical Hypertension

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The objective of this cross-sectional study was to investigate risk markers indicating the presence of albuminuria in patients with hypertension in rural sub-Saharan Africa (SSA). Urine albumin-creatinine ratio, glycated hemoglobin (HbA 1c ), blood pressure, anthropometry, and other patient characteristics including medications were assessed. We identified 160 patients with hypertension, of whom 68 (42.5%) were codiagnosed with diabetes mellitus (DM Only dysregulated DM and age were the conventional risk markers that seemed to suggest albuminuria among patients with hypertension in rural SSA. J Clin Hypertens (Greenwich).

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mentioning

confidence: 99%

Several Conventional Risk Markers Suggesting Presence of Albuminuria Are Weak Among Rural Africans With Hypertension

Rasmussen

Nordin

Thomsen

et al. 2015

J of Clinical Hypertension

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“…However, among hypertensive adults in four polyclinics in Accra, Ghana, Osafo et al [1] found a chronic kidney disease (CKD) prevalence of 46.9%. …”

Section: Introductionmentioning

confidence: 99%

State of Renal Replacement Therapy Services in Ghana

Antwi¹

2015

Blood Purif

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Introduction: Renal replacement therapy (RRT) in the form of dialysis and kidney transplantation is a life-saving intervention for patients with kidney disease in failure for both acute and chronic cases. Ghana is an emerging economy in West Africa with close to 27 million people. The limited data that is available indicates a significant burden of kidney disease in Ghana. I analyzed the state of RRT in Ghana in this report. Method: A situational analysis report conducted to establish the availability and type of renal replacement therapy services across the country. Information was obtained from records at dialysis centers and also by interview of staff at these centers. Results: Haemodialysis services are available in 3 public and 3 private health institutions for adults in kidney failure both acute and chronic. These centers are located in the southern half of the country leaving the northern two-thirds uncovered. National Health Insurance Scheme pays for the cost of acute dialysis for up to GHC 850 (∼USD 265). However, there is no insurance cover for any aspect of chronic RRT putting huge financial constraints on families, which sometimes plunge entire extended families into serious financial crisis. Kidney transplantation is available on a limited scale at the national capital. Children only benefit from peritoneal dialysis for acute kidney injury, thanks to the partnership with Sustainable Kidney Care Foundation. There is no rescue intervention as of now for children with end stage renal failure. Conclusion: The current state of RRT services in Ghana is inadequate and calls for serious national consideration.

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“…Chronic kidney disease (CKD) is a common complication of hypertensive patients in Ghana, with a prevalence ranging between 22%-46.9% among the general population [7,8]. Kidney disease and preeclampsia however, are caused by similar factors; both disorders have been linked to hypertension, obesity, insulin resistance and endothelial dysfunction [9][10][11][12][13][14][15].…”

Section: Introductionmentioning

confidence: 99%

CKD-EPI is a Better Tool for Detecting Renal Dysfunction in Hypertensive Pregnancy: A Case-Control Study in Ghana

Fondjo¹,

Wkba²,

Sakyi³

et al. 2018

Vasc Med Surg

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BackgroundPregnancy-Induced Hypertension (PIH) is a universal problem and its global incidence is estimated between 5-14% of all pregnancies [1,2]. It is one of the major causes of pregnancy-related maternal deaths in the United States [3]. In Ghana, PIH contributes 40% of all maternal deaths [4] and one of the commonest pregnancy related complication encountered in Ghanaian hospitals.Pregnancy-Induced Hypertension is the main cause of renal impairment especially acute kidney injury in late pregnancy, with reported incidence of between 2% and 11.3% in preeclampsia and eclampsia patients [5,6]. Chronic kidney disease (CKD) is a common complication of hypertensive patients in Ghana, with a prevalence ranging between 22%-46.9% among the general population [7,8]. Kidney disease and preeclampsia however, are caused by similar factors; both disorders have been linked to hypertension, obesity, insulin resistance and endothelial dysfunction [9][10][11][12][13][14][15].A strong correlation exists between the incidence of preeclampsia and later incidence of kidney disease; moreover, preeclampsia further increases the risk for developing End-Stage Renal Disease (ESRD) [16]. Screening for renal impairment in pregnant women is not performed routinely during antenatal visits as such there is scanty information on this condition in these categories of women.Renal equations have been widely accepted for use in the general population to offset the challenges associated with the use of the collection of 24-hour urine for the calculation of creatinine clearance.However, the use of these equations in pregnant women still requires validation from large sample size and across different populations.This study thus, assessed renal function in women presenting with hypertensive pregnancy using renal equations, which eliminates the cumbersome nature of requesting for 24-hour urine, with the aim of providing preliminary data that could influence the early diagnosis and management of CKD in women presenting with hypertensive pregnancy in Ghana and to encourage the adoption of these equations for routine renal assessment in women with hypertensive pregnancy. Materials and Methods Study design and settingThis Hospital-based case-control study was conducted at the Abstract Background: Pregnant women with hypertension are at an increased risk of renal impairment. This study assessed the use of CKD-EPI and 4v-MDRD for early diagnosis of renal impairment in pregnant women with hypertension.

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Prevalence of Chronic Kidney Disease in Hypertensive Patients in Ghana

Cited by 58 publications

References 26 publications

Several Conventional Risk Markers Suggesting Presence of Albuminuria Are Weak Among Rural Africans With Hypertension

Several Conventional Risk Markers Suggesting Presence of Albuminuria Are Weak Among Rural Africans With Hypertension

State of Renal Replacement Therapy Services in Ghana

CKD-EPI is a Better Tool for Detecting Renal Dysfunction in Hypertensive Pregnancy: A Case-Control Study in Ghana

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