2011
DOI: 10.1590/s0004-28032011000200009
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Abstract: -Context -Celiac disease, one of the best-known autoimmune human leukocyte antigen-dependent disorders, has a relatively increased prevalence in first-degree relatives. Objective -To determine the prevalence of celiac disease in siblings of patients with confirmed celiac disease. Methods -Siblings of confirmed celiac disease patients in our center were identified and enrolled in this study. Their serum immunoglobulin A and tissue transglutaminase antibody-enzyme-linked immunosorbent assay (anti-tissue transglu… Show more

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Cited by 10 publications
(20 citation statements)
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References 31 publications
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“…Forty-eight studies were included in this part of analysis as they reported serological prevalence among FDRs with one index case of CD ( 9,(11)(12)(13)(14)(30)(31)(32)(33)(34)(35)(36)39,(41)(42)(43)(44)(45)(46)(47)(48)(49)(50)(52)(53)(54)(55)(56)(57)(58)(59)(60)(63)(64)(65)(66)(67)(68)(69)(70)(71)(72)(73)(74)(75)(76)(77)(78). Overall, of 14,225 FDRs screened using AEA and/or anti-tTG Ab, 1,016 FDRs were seropositive ( 9,(11)…”
Section: Pooled Seroprevalence Of CD In Fdrsmentioning
confidence: 99%
“…Celiac disease (CD) is an immune-mediated enteropathy that is caused by a permanent sensitivity to gluten by taking nutrients like wheat, barley, and also rye in genetically sensitive people (13,28,47) . CD was historically believed an intestinal disorders of childhood and adult life, characterised by failure to thrive, malabsorption, diarrhea, weight loss, vomiting, unusual stools, and also abdominal distention (12,38) .…”
Section: Introductionmentioning
confidence: 99%
“…Depending on the age and pubertal status, most children will experience a catch up phase where their growth potential may be realized. However, older children who have passed puberty are unlikely to grow if their growth phase has ended [11][12][13][14][15][16][17][18][19].…”
Section: Celiac Disease Screeningmentioning
confidence: 99%
“…Biopsy confirmation is crucial, given the lifelong nature of the disease and the attendant need for an expensive and socially inconvenient diet. Although no studies have examined the number of biopsies required for diagnosis, we believe that at least four to six endoscopic-biopsy specimens should be obtained from the duodenum, given the patchy nature of the disease and the difficulty of orienting the small pieces of tissue taken during biopsy for assessment of villous morphology [13][14][15][16][17][18][19][20][21][22]. Causes of villous atrophy other than celiac disease are shown in Table 2 [23,24,25].…”
Section: Celiac Disease Screeningmentioning
confidence: 99%
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