2004
DOI: 10.4269/ajtmh.2004.71.93
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Abstract: In serum samples obtained from all the healthy humans, horses, dogs, and donkeys present on three farms in the Pedreira Municipality, an endemic area for Brazilian spotted fever, an indirect immunofluorescence assay (IFA) detected antibodies against Rickettsia rickettsii in 17 (77.3%) horses, 5 (31.3%) dogs (titers ranging from 64 to 4,048), and none of 4 donkeys or 50 humans. Five canine and eight equine sera with high antibody titers to R. rickettsii were also tested by IFA against R. bellii, R. akari, and R… Show more

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Cited by 149 publications
(218 citation statements)
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“…Although other species of Rickettsia have been described in the Brazilian territory, as Rickettsia parkeri (Horta et al 2004 and Rickettsia felis (Cardoso et al 2006, Oliveira et al 2008, only R. rickettsii has been identified in BSF human cases.…”
Section: Introductionmentioning
confidence: 99%
“…Although other species of Rickettsia have been described in the Brazilian territory, as Rickettsia parkeri (Horta et al 2004 and Rickettsia felis (Cardoso et al 2006, Oliveira et al 2008, only R. rickettsii has been identified in BSF human cases.…”
Section: Introductionmentioning
confidence: 99%
“…Each of the absorbed sera was then tested by IFA to either R. parkeri or R. rickettsii crude antigens. If serum absorbed with one Rickettsia species showed no or minimal reaction against both antigens, and a strong reaction to only one of the two antigens when absorbed with the second Rickettsia species, this serum was considered to contain antibodies stimulated by the Rickettsia species (or a very closely related species) that elicited the strong reaction in the second cross-absorption and had absorbed all the antibodies in the first reaction 6 . After absorption with R. rickettsii, the serum demonstrated a 1,024 titer against R. parkeri and no antibodies against R. rickettsii, but after absorption with R. parkeri, there was no reaction against either of the two Rickettsia antigens.…”
Section: Case Reportsmentioning
confidence: 99%
“…Além disso, é uma das mais importantes doenças rickettsiais no Brasil (Horta et al, 2004). É causada por rickettsias do grupo da febre maculosa (GFM) e tem como principal agente causal Rickettsia rickettsii, responsável também pela febre maculosa das Montanhas Rochosas (FMMR) nos Estados Unidos da América (Paddock, 2002).…”
unclassified
“…É causada por rickettsias do grupo da febre maculosa (GFM) e tem como principal agente causal Rickettsia rickettsii, responsável também pela febre maculosa das Montanhas Rochosas (FMMR) nos Estados Unidos da América (Paddock, 2002). Outras rickettsias do GFM têm sido isoladas, no Brasil, em carrapatos e pulgas, entre elas a R. belli (Horta et al, 2004), R. parkeri (Silveira et al, 2007) e R. felis (Sangioni, 2003). Embora o antígeno mais utilizado em inquéritos sorológicos no Brasil seja o de R. rickettsii, pesquisas recentes (Silveira et al, 2007) revelaram a presença de R. parkeri no Brasil, a qual tem sido comprovada como causadora de febre maculosa nos Estados Unidos, e possivelmente no Uruguai (Paddock, 2005 (Labruna et al, 2002), especialmente nas fases de larva e ninfa (Lemos et al, 1996), que usualmente fazem o repasto sanguíneo em cães, equinos, capivaras, antas e humanos (Labruna et al, 2002;Paddock et al, 2002).…”
unclassified