Prevalence and Risk Factors of Hookworm-Related Cutaneous Larva Migrans (HrCLM) in a Resource-Poor Community in Manaus, Brazil

Reichert, Felix; Pilger, Daniel; Schuster, Angela; Lesshafft, Hannah; Oliveira, Silás Guedes de; Ignatius, Ralf; Feldmeier, Hermann

doi:10.1371/journal.pntd.0004514

Cited by 23 publications

(41 citation statements)

References 38 publications

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“… 34 , 63 , 70 , 75 , 95 , 96 The presence of animal feces in household compounds has been associated with diarrhea, lower HAZ, and HrCLM. 38 , 41 , 74 Contact with manure has also been associated with the presence of antibodies to C. jejuni and pathogenic E. coli. ( 28 )…”

Section: Pathways Of Exposure To Animal Fecesmentioning

confidence: 99%

Exposure to Animal Feces and Human Health: A Systematic Review and Proposed Research Priorities

Penakalapati

Swarthout

Delahoy

et al. 2017

Environ. Sci. Technol.

281

275

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Humans can be exposed to pathogens from poorly managed animal feces, particularly in communities where animals live in close proximity to humans. This systematic review of peer-reviewed and gray literature examines the human health impacts of exposure to poorly managed animal feces transmitted via water, sanitation, and hygiene (WASH)-related pathways in low- and middle-income countries, where household livestock, small-scale animal operations, and free-roaming animals are common. We identify routes of contamination by animal feces, control measures to reduce human exposure, and propose research priorities for further inquiry. Exposure to animal feces has been associated with diarrhea, soil-transmitted helminth infection, trachoma, environmental enteric dysfunction, and growth faltering. Few studies have evaluated control measures, but interventions include reducing cohabitation with animals, provision of animal feces scoops, controlling animal movement, creating safe child spaces, improving veterinary care, and hygiene promotion. Future research should evaluate: behaviors related to points of contact with animal feces; animal fecal contamination of food; cultural behaviors of animal fecal management; acute and chronic health risks associated with exposure to animal feces; and factors influencing concentrations and shedding rates of pathogens originating from animal feces.

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Section: Pathways Of Exposure To Animal Fecesmentioning

confidence: 99%

Exposure to Animal Feces and Human Health: A Systematic Review and Proposed Research Priorities

Penakalapati

Swarthout

Delahoy

et al. 2017

Environ. Sci. Technol.

281

275

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“…It is caused by the larvae of dog or cat hookworms such as Ancylostoma caninum and Ancylostoma braziliense [ 8 ]. Even though the global burden of CLM is unknown, a prevalence as high as 18.2% has been reported in Brazil [ 9 ]. The situation of the infection in Sub-Saharan Africa (SSA), especially in Cameroon, is still obscure.…”

Section: Discussionmentioning

confidence: 99%

“…The larvae penetrate the human’s (the accidental host) skin on direct contact and secrete proteases and hyaluronidases to ease their migration and penetration through the epidermis [ 8 , 20 ]. However, the larvae of species such as Ancylostoma braziliense are incapable of attaining the dermis as they lack specific collagenases [ 9 , 21 ]; hence, they wander in the epidermis, producing the pathognomonic serpiginous tracks [ 1 , 22 ].…”

Section: Discussionmentioning

confidence: 99%

An unusual case of extensive truncal cutaneous larva migrans in a Cameroonian baby: a case report

Tianyi

Agbor²,

Kadia³

et al. 2018

J Med Case Reports

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BackgroundCutaneous larva migrans is a neglected zoonotic helminthic disease which is paradoxically underreported in low-income and middle-income countries from where a majority of the cases emanate. It presents as migratory, raised, erythematous serpentine lesions, responsive to treatment with antihelminthics. It is common in children, but rare in babies. We report an unusual case of cutaneous larva migrans in a Cameroonian baby.Case presentationWe report the case of a 9-month-old Cameroonian baby girl, whose mother had the habit of drying the child’s clothes on the grass in her courtyard. The child was brought to our hospital after she developed itchy, snake-like, slowly progressing lesions on her abdomen and chest. An examination revealed multiple raised serpentine and erythematous skin lesions consistent with cutaneous larva migrans which subsided on antihelminthic and antihistaminic therapy.ConclusionsCutaneous larva migrans is an endemic disease with predilection for poor and vulnerable persons. Preventive efforts such as wearing of slippers, usage of drying lines, and deworming of pets are crucial in preventing the occurrence of this disease and should be encouraged.

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“…The most common parasites are Ancylostoma braziliense and Ancylostoma caninum. The injuries cause intense pruritus and tortuous eruptions resulting from the penetration of the infective larvae into the human skin (REICHERT et al, 2016;REICHERT et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Occurrence of endoparasites with zoonotic potential in the city of Uruguaiana-RS

Paim

Gallina

Vidor

et al. 2019

AVB

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Article history The presence of feces of companion animals in public squares contaminated with endoparasite eggs with zoonotic potential plays a fundamental role in the transmission of diseases to the population. In this context, Cutaneous Larva Migrans and Visceral Larva Migrans are important zoonosis. In the city of Uruguaiana-RS, as well as in the national panorama, there is a shortage of data that contemplate the current contamination of public areas in order to map critical areas for the implementation of public policies to prevent these diseases. Thus, we evaluated the occurrence of endoparasites in the public squares of Uruguaiana-RS through the collection of feces in these places. A total of 87 fecal samples were collected, in which 23 were positive for endoparasite eggs with zoonotic potential. In the compilation of the data, we found higher prevalence of Ancylostoma spp. than Toxocara spp. in not fenced public squares. Compared with previous studies, a decrease in contamination of feces found and collected was observed. Thus, possible causes and suggested preventive measures were raised, as well as responsible ownership and health education to reduce environmental contamination of the city.

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Prevalence and Risk Factors of Hookworm-Related Cutaneous Larva Migrans (HrCLM) in a Resource-Poor Community in Manaus, Brazil

Cited by 23 publications

References 38 publications

Exposure to Animal Feces and Human Health: A Systematic Review and Proposed Research Priorities

Exposure to Animal Feces and Human Health: A Systematic Review and Proposed Research Priorities

An unusual case of extensive truncal cutaneous larva migrans in a Cameroonian baby: a case report

Occurrence of endoparasites with zoonotic potential in the city of Uruguaiana-RS

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