Prevalence and Risk Factors of Gastroesophageal Reflux Among Jazan University Students, Saudi Arabia: A Cross-Sectional Study

Association between physical activity and risk of gastroesophageal reflux disease: A systematic review and meta-analysis

“…Finally, 33 studies were deemed eligible for data extraction and inclusion in this systematic review and meta-analysis. 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 Among these, data from 22 articles conformed to the definition of GERD in the context of the current study. 30 , 31 , 33 , 34 , 36 , 40 , 41 , 42 , 43 , 44 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 A flowchart illustrating the study selection process is shown in Fig.…”

“…Two studies adopted a case-control design, 34 , 51 4 studies adopted a cohort study design, 29 , 46 , 47 , 61 and the remaining studies were cross-sectional. 30 , 31 , 32 , 33 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 48 , 49 , 50 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 The sample sizes of the individual studies ranged from 211 to 50,001, with a total of 66,098 cases of symptomatic GER (including 14,192 cases of GERD) and 167,855 participants across all included studies. In terms of GERD diagnosis, 4 studies relied on physician diagnosis, 34 , 40 , 50 , 51 5 studies used the Montreal definition, 41 , 43 , 44 , 52 , 53 and 13 studies employed authoritative questionnaires for diagnosis.…”

“…In terms of GERD diagnosis, 4 studies relied on physician diagnosis, 34 , 40 , 50 , 51 5 studies used the Montreal definition, 41 , 43 , 44 , 52 , 53 and 13 studies employed authoritative questionnaires for diagnosis. 30 , 31 , 33 , 36 , 42 , 48 , 49 , 54 , 55 , 56 , 57 , 58 , 59 The results of the quality assessment analyses were presented in Supplementary Tables 3 and 4 . Most studies were assessed as having a low-to-medium risk of bias.…”

“…Eight studies 30 36 , 42 , 51 , 54 , 56 , 57 , 59 with more than 2 categories of PA time were included in the dose–response analysis, comprising a total of 7806 participants (2794 cases with GERD). The analysis uncovered a linear relationship between PA duration and GERD prevalence ( χ 2 test; p = 0.004, Akaike information criterion = −8.17).…”