Prevalence and Management of Cholelithiasis in Population of Rajasthan: A Clinical Study

Sarda, Dinesh

doi:10.18535/jmscr/v6i2.27

Cited by 2 publications

(4 citation statements)

References 13 publications

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“…The M: F ratio is 1:1.6. Numerous studies confirmed what we found in our research: females had a higher prevalence of cholelithiasis than males [ 19 - 22 ]. Because of sex hormones and pregnancy, women are thought to be at higher risk, and traditional epidemiologic studies corroborate this.…”

Section: Discussionsupporting

confidence: 92%

“…Ghadhban et al stated that 84 (81.6%) of the patients who underwent testing were female, and 19 (18.4%) were male showing a 1:5 male-to-female ratio [ 18 ]. Sarda et al, Raju et al, and Sachdeva et al showed similar results as our study showing slight preponderance with the female gender in the incidence of cholelithiasis [ 19 - 21 ]. The studies by Hassan et al, Singh et al, and Ghadhban et al showed a strong association between the female gender and the prevalence of cholelithiasis [ 16 , 18 , 22 ] similar to our study (Table 7 ).…”

Section: Discussionsupporting

confidence: 90%

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Correlation Between Hypothyroidism and Gallstone Disease in Central India

Kulkarni,

Ramteke,

Lamture

et al. 2024

Cureus

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Introduction The decreased thyroid-stimulating hormone (TSH) levels affect almost every nucleated cell in our body, which directly affects the basal metabolic rate (BMR). It tends to affect multiple organ systems in the human body. In recent times, there have been changes in lifestyle and the consumption of processed foods has increased. Thus, cholelithiasis and hypothyroidism are being encountered frequently, even in rural populations. In recent times, the overt clinical presentation of hypothyroidism is rare due to early diagnosis and treatment of the subclinical hypothyroidism state itself. Aim The aim is to determine the correlation between cholelithiasis and hypothyroidism. Methods This was a cross-sectional study done on the patients presenting to the surgical department at Acharya Vinoba Bhave Rural Hospital affiliated to Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha, Maharashtra, India between the duration from December 2020 to December 2022, having gallstone disease or with symptoms suggestive of gall bladder stones. The admitted patients were then evaluated for hypothyroidism by thyroid profile tests, and the results were documented. Using the collected data, factors such as clinical spectrum, correlation between cholelithiasis and hypothyroidism, relation with the demographic data, and body mass index (BMI) were studied. Results A total of 52 gallstone patients were included in the study. A greater number of patients were found to be above the age of 40 years (82.7%), with female preponderance (61.5%). More patients with cholelithiasis were from the group with having BMI more than normal (57.6%). More patients having both cholelithiasis and hypothyroidism were also from the group with having BMI more than normal. Most symptomatic patients complained of pain in the right hypochondriac region (88.5%). Of these 52 patients, nine (17.3%) were found to have hypothyroidism (seven were subclinical, two patients had overt clinical symptoms and signs) and the remaining 43 patients were euthyroid. Conclusions Our study supports that there is a correlation between cholelithiasis and hypothyroidism. Out of all the 52 patients, nine had hypothyroidism, seven were subclinical, and two had overt symptoms. Thus, we conclude that there is a correlation between cholelithiasis and hypothyroidism.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 90%

Correlation Between Hypothyroidism and Gallstone Disease in Central India

Kulkarni,

Ramteke,

Lamture

et al. 2024

Cureus

View full text Add to dashboard Cite

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“…In this study, 40 of the 72 cases were female, with the remaining 32 being male. Several authors [9][10][11][12] have confirmed that females had a greater prevalence of cholelithiasis than males, as seen in our study. Maternity and sex hormones are thought to put women at greater risk, and some traditional epidemiologic studies back this up.…”

Section: Sexsupporting

confidence: 90%

“…Sarda et al stated that among the patients consuming vegetarian and non-vegetarian diets, gallstones were found to be more common, accounting for 80%of the cases with mixed dietary habits [30]. As far as dietary habits were concerned, 13.89% of our patients were vegetarians and 86.11% consumed mixed diet.…”

Section: Dietary Habitmentioning

confidence: 55%

Demographic and Risk Factor Profile in Patients of Gallstone Disease in Central India

Patel¹,

Yeola²,

Mahakalkar³

2022

Cureus

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BackgroundGallbladder stones are more common in some regions of the world than others. Gallstones that are asymptomatic might be discovered as an afterthought during a regular ultrasound scan for another abdominal ailment. The changing incidence in India is mostly due to westernization and the availability of ultrasonography in both urban and rural areas, as well as increased affordability owing to changes in the socio-economic structure and the budget of investigations. This study aims to know the prevalence of gallstone disease as well as the risk factors that contribute to its development in central India. MethodA single-center, cross-sectional observational study was conducted. Seventy-two radiologically diagnosed cases of gallstone disease irrespective of age, gender, and comorbid condition were included in the study. ResultSeventy-two cases of gallstone were included in the research. The highest age-specific incidence of gallstone was in the fifth and sixth decades with the maximum incidence in the sixth decade. Females had a higher incidence of gallstone formation. The pain was the earliest symptom but we found that 41.67% patients had asymptomatic gallstones. A family history of gallstone disease is found positive in 69.44% of the patients who also had an increased risk of gallstone. 22.22% patient were only diabetic, 6.95% were only hypertensive and 20.83% were both diabetic + hypertensive. Comorbidity has a high prevalence of gallstone disease. Obesity has a significant link to gallstone disease, with BMI being one of the most important indicators of obesity. ConclusionThe prevalence of asymptomatic gallstones is relatively high in central India. We strongly recommend ultrasonography as a screening modality in patients with older age group, female gender, high cholesterol level, family history of gallstones, sickle cell disease, increased BMI and co-morbidities like diabetes or hypertension for early detection of gallstones formation.

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Prevalence and Management of Cholelithiasis in Population of Rajasthan: A Clinical Study

Cited by 2 publications

References 13 publications

Correlation Between Hypothyroidism and Gallstone Disease in Central India

Correlation Between Hypothyroidism and Gallstone Disease in Central India

Demographic and Risk Factor Profile in Patients of Gallstone Disease in Central India

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