Prevalence and factors associated with Premenstrual Dysphoric Disorder: A community sample of young adult women

Carvalho, Adriana Bezerra de; Cardoso, Taiane de Azevedo; Mondin, Thaíse Campos; Silva, Ricardo Azevedo da; Souza, Luciano Dias de Mattos; Magalhães, Pedro Vieira da Silva; Jansen, Karen

doi:10.1016/j.psychres.2018.06.005

Cited by 34 publications

(39 citation statements)

References 19 publications

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“…There are a number of demographic factors associated with PMDD in the community, including older age, and low socioeconomic status. PMDD is linked to a number of comorbidities, including anxiety disorders, somatoform disorders, major depressive disorder and BD ( 20 , 21 ). Females with PMDD also report higher impairment and use of health and mental health services, in addition to higher suicide attempt rates ( 20 , 22 ).…”

Section: Introductionmentioning

confidence: 99%

Comorbid Premenstrual Dysphoric Disorder and Bipolar Disorder: A Review

2021

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Bipolar disorder (BD) differs in its clinical presentation in females compared to males. A number of clinical characteristics have been associated with BD in females: more rapid cycling and mixed features; higher number of depressive episodes; and a higher prevalence of BD type II. There is a strong link between BD and risk for postpartum mood episodes, and a substantial percentage of females with BD experience premenstrual mood worsening of varying degrees of severity. Females with premenstrual dysphoric disorder (PMDD)—the most severe form of premenstrual disturbances—comorbid with BD appear to have a more complex course of illness, including increased psychiatric comorbidities, earlier onset of BD, and greater number of mood episodes. Importantly, there may be a link between puberty and the onset of BD in females with comorbid PMDD and BD, marked by a shortened gap between the onset of BD and menarche. In terms of neurobiology, comorbid BD and PMDD may have unique structural and functional neural correlates. Treatment of BD comorbid with PMDD poses challenges, as the first line treatment of PMDD in the general population is selective serotonin reuptake inhibitors, which produce risk of treatment-emergent manic symptoms. Here, we review current literature concerning the clinical presentation, illness burden, and unique neurobiology of BD comorbid with PMDD. We additionally discuss obstacles faced in symptom tracking, and management of these comorbid disorders.

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Section: Introductionmentioning

confidence: 99%

Comorbid Premenstrual Dysphoric Disorder and Bipolar Disorder: A Review

2021

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“…Results from this study are reported under the ideation section. 22 Across the 13 studies, suicidality was assessed through a variety of measures, either using clinical interviews (n = 5), standardized questionnaires (n = 3), admittance to a hospital for suicidal attempt (n = 4), or binary symptom reporting in an interview (n = 1). Of the studies that utilized structured interviews, three used variations of the CIDI, 12,24,31 while de Carvalho et al used the MINI and Alvarado-Esquivel assessed suicidal attempt and ideation using a questionnaireassisted interview.…”

Section: Assessment Of Suicidalitymentioning

confidence: 99%

“…Of the studies that utilized structured interviews, three used variations of the CIDI, 12,24,31 while de Carvalho et al used the MINI and Alvarado-Esquivel assessed suicidal attempt and ideation using a questionnaireassisted interview. 16,18,22 Of the studies that utilized standardized questionnaires, Chaturvedi et al utilized 20,27,29 PMDD and suicidality overview. The systematic review included seven studies that investigated the relationship between PMDD and suicidality.…”

Section: Assessment Of Suicidalitymentioning

confidence: 99%

Suicidal Risk in Women with Premenstrual Syndrome and Premenstrual Dysphoric Disorder: A Systematic Review and Meta-Analysis

Prasad

Wollenhaupt-Aguiar

Kidd

et al. 2021

Journal of Women's Health

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Purpose: Women with premenstrual dysphoric disorder (PMDD) and premenstrual syndrome (PMS) experience substantial functional impairment and decreased quality of life. While previous research has highlighted a relationship between premenstrual disturbances and suicide risk, no meta-analysis has been conducted to quantitatively assess the findings. Methods: A systematic review and meta-analysis was conducted by searching the literature in three databases (Pubmed, PsycINFO, and EMBASE) on July 15, 2020. Studies that assessed the relationship between suicidality (attempt, ideation, and/or plan) and premenstrual disturbance (PMDD, PMS, and/or premenstrual symptoms) were included. Results: Thirteen studies were included in the qualitative review ( n = 10 included in meta-analysis). Results revealed that women with PMDD are almost seven times at higher risk of suicide attempt (OR: 6.97; 95% CI: 2.98–16.29, p < 0.001) and almost four times as likely to exhibit suicidal ideation (OR: 3.95; 95% CI: 2.97–5.24, p < 0.001). Similarly, women with PMS are also at increased risk of suicidal ideation (OR: 10.06; 95% CI: 1.32 to −76.67, p = 0.03), but not for suicide attempt (OR: 1.85; 95% CI: 0.77 to −4.46, p = 0.17). Conclusions: Women with PMDD and PMS are at higher risk of suicidality compared with women without premenstrual disturbances. These findings support routine suicidal risk assessments for women who suffer from moderate-to-severe premenstrual disturbance. Furthermore, psychosocial treatments for women diagnosed with PMS/PMDD should consider and target suicidality to minimize risk and improve well-being.

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“…[2][3][4] In a recent study on a Brasilian community sample, the prevalence of PMDD is over 15% in young adult women, probably due to cultural differences and a wider age span. 5 PMDD is often diagnosed many years after its first onset, thus resulting in a long period of untreated symptoms, 6 with a huge impact on functioning and quality of life. 7,8 Although PMDD can be observed in women without other psychiatric disorders, 9 comorbid conditions are reported in up to 70% of cases, especially anxiety disorder, post-traumatic stress disorder, major depression and bipolar disorder (BD).…”

Section: Introductionmentioning

confidence: 99%

<p>Comorbid Premenstrual Dysphoric Disorder in Women with Bipolar Disorder: Management Challenges</p>

Sepede¹,

Brunetti²,

Giannantonio³

2020

NDT

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Bipolar disorder (BD) and premenstrual dysphoric disorder (PMDD) are two cyclic mood illnesses, sometimes presenting together. Their comorbidity appears to be linked to common biological mechanisms and usually results in more severity of mood symptoms and a poorer long-term outcome. Nevertheless, the management of comorbid PMDD/BD has been scarcely studied. Therefore, the aim of the present paper was to review the published literature on the treatment of comorbid PMDD/BD and to provide point-by-point hypotheses to address these complex clinical cases. We searched PubMed to identify the studies focused on the treatment and management of comorbid PMDD/BD using the following search words, alone and in combination: premenstrual dysphoric disorder, bipolar disorder, comorbid, treatment, management, pharmacotherapy, psychotherapy. The search was conducted on the 1st of June 2019 and yielded 55 records. Four papers met our inclusion/exclusion criteria and were therefore included in our qualitative synthesis. Integrating the few data pertaining to the treatment of comorbid PMDD/BD with the large amount of published data on the two conditions separately, we can suggest that the management of comorbid PMDD/BD needs as a first step to stabilize the bipolar symptoms by means of optimal dosages of mood stabilizers. Then, in euthymic BD patients, the PMDD symptoms could be treated with estroprogestins (first-line treatment). On the contrary, during acute phases of BD, antidepressants (for major depressive episodes) and atypical antipsychotics/hormonal modulators (for manic episodes) could be considered as promising add-on treatments to mood stabilizers. In case of resistant PMDD/BD symptoms, combined strategies should be taken into account, as well as alternative treatments, such as lifestyle changes. In conclusion, RCTs on comorbid PMDD/BD are still lacking. The management of this complex condition is therefore challenging and it requires a tailored treatment.

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Prevalence and factors associated with Premenstrual Dysphoric Disorder: A community sample of young adult women

Cited by 34 publications

References 19 publications

Comorbid Premenstrual Dysphoric Disorder and Bipolar Disorder: A Review

Comorbid Premenstrual Dysphoric Disorder and Bipolar Disorder: A Review

Suicidal Risk in Women with Premenstrual Syndrome and Premenstrual Dysphoric Disorder: A Systematic Review and Meta-Analysis

<p>Comorbid Premenstrual Dysphoric Disorder in Women with Bipolar Disorder: Management Challenges</p>

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