Prevalence and factors associated with depression in people living with HIV in sub-Saharan Africa: A systematic review and meta-analysis

Bernard, Charlotte; Dabis, François; Rekeneire, Nathalie de

doi:10.1371/journal.pone.0181960

Cited by 180 publications

(172 citation statements)

References 79 publications

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“…Even though highly active antiretroviral therapy (HAAR T) helped patients to live longer and healthier lives, it is accompanied with numerous challenges in terms of associated symptoms and treatment side effects [5][6][7]. Fatigue is one of the most frequently reported symptoms by HIV/ Acquired Immune Deficiency Syndrome (HIV/AIDS) patients [8,9], which is defined as a 'subjective sensation of weariness, increasing sense of effort, mismatch between effort expended and actual performance, or exhaustion which is not relived by additional sleep or rest' [10].…”

Section: Introductionmentioning

confidence: 99%

Burden of fatigue among adults living with HIV/AIDS attending antiretroviral therapy in Ethiopia

et al. 2020

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Background: Fatigue is one of the most common and devastating Human Immuno-deficiency Virus (HIV)-related symptoms, with a varying prevalence in different study areas. In Ethiopia, there is a paucity of information on the magnitude and factors associated with fatigue among HIV/Acquired Immune Deficiency Syndrome (AIDS) patients. This may lead to under-diagnosis and eventually under-management of the symptom. Methods: Institution based cross-sectional study design was conducted among 609 HIV/AIDS patients who were selected by using a systematic random sampling method. Data were collected by using interviewer administered structured questionnaire. Level of fatigue was measured by Fatigue Severity Scale.

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Section: Introductionmentioning

confidence: 99%

Burden of fatigue among adults living with HIV/AIDS attending antiretroviral therapy in Ethiopia

et al. 2020

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“…Depression and anxiety change over time and studies examining such conditions at a single time point will not represent their course and progression [11]. Although an overwhelming majority of cross-sectional studies have demonstrated the prevalence and related factors of depression and anxiety among people living with HIV, the results have been fragmentary and inconsistent [12][13][14][15]. Findings of the few existing longitudinal studies have also been mixed [16][17][18][19][20][21][22].…”

Section: Introductionmentioning

confidence: 99%

Longitudinal trajectories of emotional problems and unmet mental health needs among people newly diagnosed with HIV in China

et al. 2019

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Introduction Concern over mental health morbidity affecting people living with HIV is increasing worldwide. The objective of this study was to describe the longitudinal trajectories of depression and anxiety, and mental health service utilization among people newly diagnosed with HIV. Methods This was an observational cohort study that enrolled people newly diagnosed with HIV consecutively and followed them for one year in Changsha, China. Socio‐demographic, clinical and psychological data were collected at the baseline and at one‐year follow‐up. Participants were recruited between March 1, 2013 and September 30, 2014. The final follow‐up was in September 30, 2015. Results Among 557 people newly diagnosed with HIV enrolled at the baseline, 410 (73.6%) completed the one‐year follow‐up survey (median (interquartile range) age at follow‐up: 29 (25, 39) years; 376 men (91.7%)), and were included in the analysis. 39.3% and 30.2% of the 410 participants were screened with significant symptoms of depression and anxiety at baseline respectively. An overall drop in the prevalence of each condition was found at follow‐up, however, 10.5% and 6.1% of participants were found to have persistent depression and anxiety. The results of mixed‐effect models showed that bisexuality, homosexual transmission, other clinical symptoms (for example, not on antiretroviral therapy (ART)), non‐disclosure, higher levels of HIV/AIDS‐related stress, and lack of social support were associated with significant symptoms of depression and anxiety. One year after diagnosis, 8.3% had visited healthcare providers for emotional or psychological problems. Conclusions Despite the obvious need people newly diagnosed with HIV in China rarely seek professional help. Integrating depression and anxiety screening and referral into HIV care settings is warranted.

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“…Even though highly active antiretroviral therapy (HAART) helped patients to live longer and healthier lives, it is accompanied with numerous challenges in terms of associated symptoms and treatment side effects [5][6][7]. Fatigue is one of the most frequently reported symptoms by HIV/AIDS patients [8,9], which is defined as a 'subjective sensation of weariness, increasing sense of effort, mismatch between effort expended and actual performance, or exhaustion which is not relived by additional sleep or rest' [10].…”

Section: Introductionmentioning

confidence: 99%

Burden of Fatigue among Adults Living with HIV/AIDS Attending Antiretroviral Therapy in Ethiopia

Gebreyesus

Belay

Berhe

et al. 2020

Preprint

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Background: Fatigue is one of the most common and devastating HIV-related symptoms, with a varying prevalence in different study areas. In Ethiopia, there is a paucity of information on the magnitude and factors associated with fatigue among HIV/AIDS patients. This may lead to under-diagnosis and eventually under-management of the symptom.Objectives: This study assessed the prevalence and factors associated with fatigue among adults living with HIV/AIDS attending antiretroviral therapy at health facilities of Mekelle city, Tigray, North Ethiopia, 2019. Methods: Institution based cross-sectional study design was conducted among 609 HIV/AIDS patients who were selected by using a systematic random sampling method. Data were collected by using interviewer administered structured questionnaire. Level of fatigue was measured by Fatigue Severity Scale.Results: The prevalence of fatigue was found to be 51.7%. The factors associated with fatigue were: Parity [AOR= 2.01; 95% CI: 1.09-3.71], CD4 count 200-499 cells/mm3 [AOR= 2.81; 95% CI: 1.58-4.99], anemia [AOR= 4.90 95% CI: 2.40-9.97], co-morbidities [AOR= 3.65; 95% CI: 1.71-7.78], depression [AOR= 3.68 95% CI: 1.99-6.79], not being physically active [AOR= 3.20 95% CI: 1.50-6.81], clinical stage II or IV HIV [AOR= 3.11; 95% CI: 1.51-6.40] and [AOR= 4.08; 95% CI: 1.37-12.14], respectively.Conclusion: The finding of this study revealed that fatigue is a common health problem among adult PLHIV. Factors associated with fatigue included: Parity, CD4 count 200-499 cells/mm3, Clinical Stage II or IV HIV, anemia, co-morbidities, depression, and not being physically active. The health care service needs to address the predisposing factors by provision optimum care so that PLHIV can be encouraged in physical activity in order to relieve the impact of fatigue.

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Prevalence and factors associated with depression in people living with HIV in sub-Saharan Africa: A systematic review and meta-analysis

Cited by 180 publications

References 79 publications

Burden of fatigue among adults living with HIV/AIDS attending antiretroviral therapy in Ethiopia

Burden of fatigue among adults living with HIV/AIDS attending antiretroviral therapy in Ethiopia

Longitudinal trajectories of emotional problems and unmet mental health needs among people newly diagnosed with HIV in China

Burden of Fatigue among Adults Living with HIV/AIDS Attending Antiretroviral Therapy in Ethiopia

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