Pressure analysis of the blood flow in the arteriole

Abstract

Poiseuille's law relates the flow rate with the pressure, viscosity, vessel radius and length. For the purposes of this exhibit, we will assume that the vessel in consideration is a small artery or an arteriole. Specifically, the complete circulatory system has a mean pressure drop of approximately 98 mmHg and the arterioles comprise 50% of this decrease. Using the mean velocity, blood pressure gradient can be expressed in terms of the velocity of the arteriole flow. Based on Poiseuille's law, this paper presented how the blood flow depends on the pressure and diameter of arteriole.

Endothelial progenitor cell recruitment in a microfluidic vascular model

“…ECFCs that had been pretreated in a 1% oxygen environment for 24 h were then labeled using PKH26 red (Sigma Aldrich). The two million ECFC's were re-suspended in PromoCell media with 0.1% BSA and set to flow into the microfluidic device at 0.1 dyn cm −2 [28] for 45 min. This flow rate allows us to mimic a pathological pressure drop of an arteriole and the shear stress in disease states such as atherosclerosis [29].…”