volume 55, issue 3, P761-765 1990
DOI: 10.1135/cccc19900761
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Abstract: N-Protected a:-amino alcohols were prepared by reduction of N-protected a:-amino acid esters by sodium acetoxyborohydride in dioxane at elevated temperature. The reductions proceed with excellent yields and without racemisation. Reduction of the carbamate protecting groups was not observed.Optically active N-protected IX-amino alcohols, derived from natural IX-amino acids are frequently used as precursors for preparation of N-protected IX-amino aldehydes in stereocontrolled organic synthesis!. Several procedu…

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