2007
DOI: 10.1002/chin.200740160
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Atsuko Nishiguchi,
Tomomi Ikemoto,
Tatsuya Ito
et al.

Abstract: Preparation of a 1-Unsubstituted-2,3-dihydro-1-benzazepine Derivative. -An effective synthesis of the title dihydrobenzazepine derivative (VI) using an intramolecular Claisen-type condensation as the key step is developed. Compound (V) is smoothly converted into the orally active CCR5 antagonist intermediate (X). -(NISHIGUCHI*, A.; IKEMOTO, T.; ITO, T.; MIURA, S.; TOMIMATSU, K.; Heterocycles 71 (2007) 5, 1183-1192; Chem. Dev. Lab.,

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