“…In particular calcium-based nanoparticles have shown to have therapeutic benefits when used in cutaneous wound repair (Kawai et al, 2011). On the other hand, sericin has high antioxidant potential (Prasong, 2011;Kumar and Mandal, 2017), antibacterial activity (Ramesan et al, 2016), mitogenic effect on cells (Terada et al, 2005), potential to inhibit inflammation (Aramwit et al, 2012a), and ability to retain hydration (Padamwar et al, 2005). In the study of Aramwit et al, a sericin-based therapeutic cream formulation improved healing by promoting collagen production and rapid re-epithelialization in rat skin wounds (Aramwit et al, 2009(Aramwit et al, , 2013.…”