Preparation and characterization of zein/pectin-based phytosterol nanodispersions and kinetic study of phytosterol release during simulated digestion in vitro

Feng, Simin; Wang, Dan; Gan, Ling; Shao, Ping; Jiang, Ligang; Sun, Peilong

doi:10.1016/j.lwt.2020.109446

Cited by 29 publications

(8 citation statements)

References 35 publications

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“…109 According to in vitro studies, the presence of pectin can control the release of stigmasterols by improving the stability of the NPs under digestion conditions. 81,110 Fourth, Afzal revealed that positively charged chitosan facilitates the transport of β-sitosterols through the negatively charged mucous membrane and loosens the tight junction of the intestinal cells, thereby improving the permeation of the intestinal membrane and BA of β-sitosterols. 104 Fifth, indigestible dietary fiber may be fermented by microbiota in the colon to produce some metabolites that alter the metabolism, activity and absorption of lipophilic bioactive compounds in the intestine.…”

Section: Carbohydratesmentioning

confidence: 99%

Effects of food formulation on bioavailability of phytosterols: phytosterol structures, delivery carriers, and food matrices

Wang

et al. 2023

Food Funct.

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Section: Carbohydratesmentioning

confidence: 99%

Effects of food formulation on bioavailability of phytosterols: phytosterol structures, delivery carriers, and food matrices

Wang

et al. 2023

Food Funct.

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“…The zein/pectin-based phytosterol nanoparticles were prepared according to our previous work (Feng, Wang, et al, 2020). The mean particle size of phytosterol nanoparticles was measured using a particle size analyzer (Malvern ZS), and the zeta potentials of the phytosterol nanoparticles was obtained using a particle size analyzer in PALS zeta potential measurement mode.…”

Section: Zein/pectin-based Phytosterol Nanoparticles Preparation and ...mentioning

confidence: 99%

“…The microstructures of the phytosterol nanoparticle were observed using a scanning electron microscope (SEM), a transmission electron microscope (TEM), and an atomic force microscope (AFM) as described previously (Feng, Wang, et al, 2020). The interaction between zein/ pectin and phytosterols was studied using Fourier transform infrared spectroscopy (FTIR).…”

Section: Zein/pectin-based Phytosterol Nanoparticles Preparation and ...mentioning

confidence: 99%

Rice bran phytosterol nanoparticles: A promising approach to enhance yogurt quality and nutrition

Feng,

Guo,

Wang

et al. 2023

Food Bioengineering

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This study aimed to improve the comprehensive utilization value of rice bran by investigating catalysts for the methyl esterification reaction of rice bran oil deodorized distillates and preparing phytosterol nanoparticles for addition to yogurt. Fe2(SO4)3 was found to be an effective catalyst, achieving a methyl esterification rate of 98.07 ± 0.23% under optimal conditions. Then, phytosterol nanoparticles were prepared and added to yogurt, resulting in stable addition with the pH decreased from 4.23 ± 0.01 to 4.02 ± 0.01 and the titratable acidity increased from 106.48 ± 0.85 °T to 117.07 ± 0.82 °T during storage. The addition of phytosterol nanoparticles increased the apparent viscosity from 0.68 ± 0.01 Pa s to 0.72 ± 0.02 Pa s and the G* from 80.01 ± 5.50 Pa to 91.80 ± 1.99 Pa, resulting in thicker and more elastic texture. Phytosterol nanoparticle improves the dispersion and stability of phytosterols in yogurt, thus making it stable to be added to yogurt. Fe2(SO4)3 is a suitable catalyst for the methyl esterification reaction of rice bran oil deodorized distillates, and the addition of rice bran phytosterol nanoparticles to yogurt can enhance its texture and nutritional value, offering a promising strategy for producing high value‐added products from rice bran.

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“…Similarly, encapsulation of lycopene into oil-in-water nanoemulsions increased carotenoid bioaccessibility, with the efficacy increasing with decreasing droplet size [ 110 ]. Phytosterols have been encapsulated within pectin-coated zein nanoparticles, which was shown to improve their stability and to modulate their release under simulated GIT conditions [ 111 ]. Phytosterols have also been encapsulated within nanoporous starch aerogels [ 77 ], which increased their in vitro bioaccessibility when incorporated into granola bars and puddings compared to free phytosterols.…”

Section: Enhanced Bioavailabilitymentioning

confidence: 99%

Utilization of Nanotechnology to Improve the Handling, Storage and Biocompatibility of Bioactive Lipids in Food Applications

McClements

Öztürk

2021

Foods

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Bioactive lipids, such as fat-soluble vitamins, omega-3 fatty acids, conjugated linoleic acids, carotenoids and phytosterols play an important role in boosting human health and wellbeing. These lipophilic substances cannot be synthesized within the human body, and so people must include them in their diet. There is increasing interest in incorporating these bioactive lipids into functional foods designed to produce certain health benefits, such as anti-inflammatory, antioxidant, anticancer and cholesterol-lowering properties. However, many of these lipids have poor compatibility with food matrices and low bioavailability because of their extremely low water solubility. Moreover, they may also chemically degrade during food storage or inside the human gut because they are exposed to certain stressors, such as high temperatures, oxygen, light, moisture, pH, and digestive/metabolic enzymes, which again reduces their bioavailability. Nanotechnology is a promising technology that can be used to overcome many of these limitations. The aim of this review is to highlight different kinds of nanoscale delivery systems that have been designed to encapsulate and protect bioactive lipids, thereby facilitating their handling, stability, food matrix compatibility, and bioavailability. These systems include nanoemulsions, solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), nanoliposomes, nanogels, and nano-particle stabilized Pickering emulsions.

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Preparation and characterization of zein/pectin-based phytosterol nanodispersions and kinetic study of phytosterol release during simulated digestion in vitro

Cited by 29 publications

References 35 publications

Effects of food formulation on bioavailability of phytosterols: phytosterol structures, delivery carriers, and food matrices

Effects of food formulation on bioavailability of phytosterols: phytosterol structures, delivery carriers, and food matrices

Rice bran phytosterol nanoparticles: A promising approach to enhance yogurt quality and nutrition

Utilization of Nanotechnology to Improve the Handling, Storage and Biocompatibility of Bioactive Lipids in Food Applications

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