Preparation and characterization of dual stimuli-responsive microcapsules with a superparamagnetic porous membrane and thermo-responsive gates

Preparation and characterization of magnetic alginate-chitosan hydrogel beads loaded matrine

“…However, the magnetic particles must be coated with a biocompatible polymer to improve surface properties and minimize the toxic side effects when used in biological system. For application, the drug carriers are often incorporated with magnetic nanoparticles, which can transport drug directly to the centre of the disease with the aid of an external magnetic field, thereby treat it deliberately, with no effects on both normal cells and tissues 44 . After absorption by human body, the remanent magnetic particles can be safely excreted through skin, bile, kidney, etc, thus, Fe 3 O 4 magnetic nanoparticles are wide spread in medicine and pharmaceutical industries, namely in disease detection, controlled drug delivery, in tissue engineering and so on.…”

Novel cationic pH-responsive poly(N,N-dimethylaminoethyl methacrylate) microcapsules prepared by a microfluidic technique

“…Environment-responsive microcapsules are capable of changing their physical-chemical properties and colloidal properties in response to various external stimuli such as temperature [1][2][3][4][5], pH [6][7][8][9][10], magnetic field [11,12] and so on. Due to their ''smart'' responsive abilities and certain advantages such as small size, huge total surface area, large inner volume, and stable membrane, environment-responsive microcapsules have attracted great interests in recent years in therapeutical and biotechnological fields, such as drug delivery systems [13][14][15], biosensors [16], chemical separations [17], and so on.…”

Preparations and temperature-dependent release properties of Pluronic F127-containing microcapsules prepared by a double emulsion technique

“…As a result, the blood concentration of drug increases rapidly to a toxic level in the early stage after administration, and then it immediately decreases to a non-therapeutic level. To circumvent the shortcomings of the conventional carriers, recent researches have been exerted to obtain a zero order release by using a reservoir type of microcapsule [1][2][3][4] and a biodegradable microsphere [5][6][7]. Carriers responsive to environmental pH have been developed for the application in cancer treatment [8], type I diabetes treatment [9][10][11], and oral vaccination [12], and intestine-specific delivery [13].…”