2018
DOI: 10.1590/1980-5373-mr-2017-0951
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Preparation and Characterization of Chitosan/mPEG-PCL Blended Membranes for Wound Dressing and Controlled Gentamicin Release

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Cited by 11 publications
(8 citation statements)
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“…The PCL fibers' spectra indicate a strong sharp peak around 1717 cm −1 , which is due to C=O vibration and at 2942 cm −1 which represented a C-H peak [50]. Moreover, several characteristic bands of PCL were found at 2949 cm -1 (asymmetric -CH 2 stretching), 2865 cm −1 (symmetric -CH 2 stretching), 1726 cm −1 (carbonyl stretching), 1293 cm −1 (C-O and C-C stretching), 1240 cm −1 (asymmetric C-O-C stretching), and 1170 cm −1 (symmetric C-O-C stretching) [35,36] (Figure S1).…”
Section: Fourier Transform Infrared Spectroscopymentioning
confidence: 98%
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“…The PCL fibers' spectra indicate a strong sharp peak around 1717 cm −1 , which is due to C=O vibration and at 2942 cm −1 which represented a C-H peak [50]. Moreover, several characteristic bands of PCL were found at 2949 cm -1 (asymmetric -CH 2 stretching), 2865 cm −1 (symmetric -CH 2 stretching), 1726 cm −1 (carbonyl stretching), 1293 cm −1 (C-O and C-C stretching), 1240 cm −1 (asymmetric C-O-C stretching), and 1170 cm −1 (symmetric C-O-C stretching) [35,36] (Figure S1).…”
Section: Fourier Transform Infrared Spectroscopymentioning
confidence: 98%
“…PCL and PCL/CUR casting films were prepared using PCL and PCL/CUR solutions obtained in Section 2.2. The membranes were obtained by casting 1.5 mL of each solution in a circular mold (diameter 2.5 cm), followed by the evaporation of solvent at room temperature according to Brianezi et al [35].…”
Section: Preparation Of Pcl/cur Cast Filmsmentioning
confidence: 99%
“…All gentamicin-loaded membranes inhibited S. aureus and E. coli growth, and demonstrated color, moisture and thermal stability. Therefore, mPEG-PCL/CHI-genipin membranes showed important features for potential wound dressing and drug delivery applications [132] . An interesting tissue-engineered skin substitute, based on gelatin, collagen, and PCL, was fabricated by impregnation of lyophilized gelatin/collagen (GC) mats with PCL solutions, followed by solvent evaporation.…”
Section: Biomaterials For Wound Managementmentioning
confidence: 99%
“…Another alternative to improve the miscibility of gentamicin with PVA and chitosan is by chemically modifying the polymer backbone or adding molecules that consists of both hydrophobic and hydrophilic moieties (i.e. surfactant) [31]. The diameter of the nanofibers and the drug's physical properties such as solubility and drug-polymer interactions may significantly affect the drug release rate [28].…”
Section: In Vitro Drug Release Studymentioning
confidence: 99%