Preparation and antibacterial property on silver incorporated mesoporous bioactive glass microspheres

Phetnin, Ratiya; Rattanachan, Sirirat

doi:10.1007/s10971-015-3697-1

Cited by 43 publications

(10 citation statements)

References 32 publications

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“…For example, calcium (Ca) ions can accelerate blood coagulation. 6 MBGs with silver (Ag) ions can be antibacterial [7][8][9] against Gramnegative and Gram-positive bacteria even at 0.02 wt % Ag. MBGs with europium (1-5 mol %) have shown significant bone formation stimulation in an in vivo rat model.…”

Section: Introductionmentioning

confidence: 99%

The effect of tantalum incorporation on the physical and chemical properties of ternary silicon–calcium–phosphorous mesoporous bioactive glasses

et al. 2019

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Synthesis and characterization of the first mesoporous bioactive glasses (MBGs) containing tantalum are reported here, along with their potential application as hemostats. Silica MBGs were synthesized using with the molar composition of (80‐x)% Si, 15% Ca, 5% P, and x% Ta. It was found that incorporation of >1 mol % Ta into the MBGs changes their physical and chemical properties. Increasing Ta content from 0 to 10 mol % causes a decrease in the surface area and pore volume of ~20 and ~35%, respectively. This is due to the increase in nonbridging oxygens and mismatch of thermal expansion coefficient which created discontinuities in the ordered channel structure. However, the effect is not significant on the amount of ions (Si, Ca, P, and Ta) released, from the sample into deionized water, for short durations (<60 min). In a mouse tail‐cut model, a significant decrease in bleeding time (≥50% of average bleeding time) was found for Ta‐MBGs compared to having no treatment, Arista, and MBG without Ta. Further studies are proposed to determine the mechanism of Ta involvement with the hemostatic process. © 2019 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 107B: 2229–2237, 2019.

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Section: Introductionmentioning

confidence: 99%

The effect of tantalum incorporation on the physical and chemical properties of ternary silicon–calcium–phosphorous mesoporous bioactive glasses

et al. 2019

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“…[7,13] 5Ag‐SMBG, with silver as antibacterial addition, was synthesized by the sol‐gel method as reported in our previous work. [12] The diameter of the particle ranged from 2 to 30 μm. MBG, SMBG, and 5Ag‐SMBG presented a relative narrow pore size distribution, and the average pore diameters of all samples were between 4.3 and 5.3 nm which could be used as biological protein molecules or drug carriers.…”

Section: Methodsmentioning

confidence: 99%

“…In our study, mesoporous bioactive glasses, composed of 80 mol% SiO 2 ‐15 mol% CaO‐5 mol% P 2 O 5 with different morphologies, were synthesized by the sol‐gel method as previously described. [12] The irregular mesoporous bioactive glass (MBG), spherical mesoporous bioactive glass (SMBG), and 5% antibacterial doped mesoporous bioactive glass (5Ag‐SMBG), were dispersed in SF/CS‐based scaffolds before fabrication by lyophilization. Their characteristics, mechanical properties, and in vitro activity were finally investigated.…”

Section: Introductionmentioning

confidence: 99%

3D mesoporous bioactive glass/silk/chitosan scaffolds and their compatibility with human adipose‐derived stromal cells

Phetnin

Suksaweang

Giannasi

et al. 2020

Int J Applied Ceramic Tech

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Human adipose-derived stem/stromal cells (hASCs) have been popularly studied as cell-based therapy in the field of regenerative medicine due to their ability to differentiate into several cell types. In this study, in order to improve the mechanical strength and bioactivity of scaffolds for bone tissue engineering, three types of mesoporous bioactive glasses with different shapes and compositions were dispersed in the silk fibroin/chitosan (SF/CS)-based scaffolds, which were fabricated with a combination of freezing and lyophilization. The characteristic and physical properties of these composite scaffolds were evaluated. The biocompatibility was also assessed through hASCs in vitro tests. Both Alamar Blue® and Live/Dead assay® revealed that the spherical mesoporous bioactive glass doped scaffolds enhanced cell viability and proliferation. Furthermore, the addition of spherical mesoporous bioactive glass into SF/CS scaffolds encouraged hASC osteogenic differentiation as well. These results suggested that this composite scaffold can be applicable material for bone regeneration. K E Y W O R D S bioactive glass, chitosan, composite scaffold, human adipose-derived stem/stromal cells, silk fibroin, tissue engineering 2780 | PHETNIN ET al. How to cite this article: Phetnin RB, Suksaweang S, Giannasi C, et al. 3D mesoporous bioactive glass/silk/ chitosan scaffolds and their compatibility with human adipose-derived stromal cells.

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“…Meanwhile, another research group (Phetnin & Rattanachan, 2015) prepared a silver‐incorporated mesoporous bioactive glasses microsphere with different silver contents (1, 3, and 5 mol%) using low temperature sol‐gel method. The prepared mesoporous bioactive glass (80SiO 2 .…”

Section: Applications Of Metal Nanomaterials For Bone Tissue Engineeringmentioning

confidence: 99%

Metal‐based nanoparticles for bone tissue engineering

Eivazzadeh‐Keihan

Noruzi

Chenab

et al. 2020

J Tissue Eng Regen Med

139

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Tissue is vital to the organization of multicellular organisms, because it creates the different organs and provides the main scaffold for body shape. The quest for effective methods to allow tissue regeneration and create scaffolds for new tissue growth has intensified in recent years. Tissue engineering has recently used some promising alternatives to existing conventional scaffold materials, many of which have been derived from nanotechnology. One important example of these is metal nanoparticles. The purpose of this review is to cover novel tissue engineering methods, paying special attention to those based on the use of metal‐based nanoparticles. The unique physiochemical properties of metal nanoparticles, such as antibacterial effects, shape memory phenomenon, low cytotoxicity, stimulation of the proliferation process, good mechanical and tensile strength, acceptable biocompatibility, significant osteogenic potential, and ability to regulate cell growth pathways, suggest that they can perform as novel types of scaffolds for bone tissue engineering. The basic principles of various nanoparticle‐based composites and scaffolds are discussed in this review. The merits and demerits of these particles are critically discussed, and their importance in bone tissue engineering is highlighted.

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Preparation and antibacterial property on silver incorporated mesoporous bioactive glass microspheres

Cited by 43 publications

References 32 publications

The effect of tantalum incorporation on the physical and chemical properties of ternary silicon–calcium–phosphorous mesoporous bioactive glasses

The effect of tantalum incorporation on the physical and chemical properties of ternary silicon–calcium–phosphorous mesoporous bioactive glasses

3D mesoporous bioactive glass/silk/chitosan scaffolds and their compatibility with human adipose‐derived stromal cells

Metal‐based nanoparticles for bone tissue engineering

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