Preoperative diffusion-weighted imaging value of rectal cancer: preoperative T staging and correlations with histological T stage

Comparison of reduced field‐of‐view diffusion‐weighted imaging (DWI) and conventional DWI techniques in the assessment of rectal carcinoma at 3.0T: Image quality and histological T staging

“…Regarding the relationship between ADC values and histological T staging of rectal cancer, we observed a significant tendency for an inverse correlation between the ADC values of the two different DWI methods and the T stage. Lu et al 35 also reported that the ADC values of the fDWI technique were significantly correlated with the corresponding T stages of rectal cancer. In addition, a diminished trend for ADC values was noted from the T2 to T4 stages, which is consistent with our data.…”

“…Higher T stage indicates tumor cells of rectal cancer with a higher malignant degree, resulting in a microenvironment with a greater tumor cell density and other tumor components. Thus, the diffusion movement of water molecules is more restricted, and ADC values are reduced . Accordingly, the ADC values for both DWI methods might be associated with the inherent aggressiveness of particular tumor tissues, including rectal cancer.…”

“…Thus, the diffusion movement of water molecules is more restricted, and ADC values are reduced. 35 Accordingly, the ADC values for both DWI methods might be associated with the inherent aggressiveness of particular tumor tissues, including rectal cancer.…”

Feasibility of Simultaneous Multislice Acceleration Technique in Diffusion-Weighted Magnetic Resonance Imaging of the Rectum

“…In rectal cancer patients, magnetic resonance imaging (MRI) is the primary imaging modality, principally due to its exceptionally excellent soft tissue Feasibility of Simultaneous Multislice Acceleration Technique in Diffusion-Weighted Magnetic Resonance Imaging of the Rectum contrast in T2-weighted imaging (2,3). In addition to T2weighted imaging, diffusion-weighted imaging (DWI), a functional MRI technique, helps not only in detecting and characterizing lesions, but also in predicting the therapeutic response in rectal cancer (4)(5)(6)(7)(8). Furthermore, because DWI does not require intravenous contrast administration, it is generally implemented as part of a routine MRI protocol in evaluation of rectal cancer (9).…”

Comparison of T and N Staging on Preoperative Magnetic Resonance Imaging and Postoperative Histopathologic Specimens in Rectum Cancer

“…However, for the other stages, the T3 and T4 groups showed the highest MRI/histopathology agreement, while we were detecting early stage cancers was unsuccessful. Lu et al 15 found it most difficult to distinguish T2 and T3 tumors using MRI and reported that high-resolution MRI may facilitate their differentiation. The T-staging accuracy rate of ERUS in rectal cancers has been reported as approximately 69%.…”