volume 93, issue 0, P3-P-304 2020
DOI: 10.1254/jpssuppl.93.0_3-p-304
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Abstract: The hypothesis of the "development origins of health and diseases" addresses the risk of chronic kidney disease in adulthood. Although prenatal glucocorticoid (GC) therapy has shown to prevent infant respiratory injury in the neonate, the effects of the kidney functions remains unknown. This study aimed to investigate whether prenatal GC administration is associated with fetal kidney maturation. Dexamethasone (DEX) was administered to pregnant rats for 2 days on days 17 and 18 or days 19 and 20 of gestation, a…

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