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Cited by 18 publications
(16 citation statements)
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“…An increase in the expression of inflammatory response genes was observed in testes of adult rats after perinatal exposure to 0.2 mg/kg of BDE-47 [34] and in testes of immature rats after prenatal exposure to 0.2 mg/kg of BDE-99 [114]. Biological categories enriched with upregulated genes included interferon, IL3 and IL5, and TNFa signaling, allograft rejection, and natural killer cell-mediated cytotoxicity among others.…”
Section: Inflammatory Responsementioning
confidence: 99%
See 1 more Smart Citation
“…An increase in the expression of inflammatory response genes was observed in testes of adult rats after perinatal exposure to 0.2 mg/kg of BDE-47 [34] and in testes of immature rats after prenatal exposure to 0.2 mg/kg of BDE-99 [114]. Biological categories enriched with upregulated genes included interferon, IL3 and IL5, and TNFa signaling, allograft rejection, and natural killer cell-mediated cytotoxicity among others.…”
Section: Inflammatory Responsementioning
confidence: 99%
“…A growing body of literature provides clear evidence that early life exposures to PBDEs at environmentally relevant doses may have long-lasting effects on mammalian tissue physiology [93,94,116,117], including male reproductive tissues [33,34,40,43,114]. Studies demonstrate that perinatal or neonatal exposures result in reduced testis weight and reduced sperm quality parameters [33,34,43,46,114].…”
Section: Developmental Programming Of Blood-testis Barrier (Btb)mentioning
confidence: 99%
“…People can be exposed by contaminated foods (mainly those with a high fat content), air or dust. Recent findings revealed that prenatal exposure to environmentally relevant levels of PBDE-99 leads to steroidogenesis disorders [ 100 ].…”
Section: The Most Common Edcsmentioning
confidence: 99%
“…With the advance of high-throughput techniques ( Goodwin et al, 2016 ), more and more researchers have started to depict molecular profiling in a systematic manner ( Cancer Genome Atlas, 2012 ; Yan et al, 2015 ; Cancer Genome Atlas Research Network. Electronic address and Cancer Genome Atlas Research, 2017 ; Wang et al, 2018 ; Zhao et al, 2022 ). Massive amounts of omics data are produced and usually require sophisticated visualization analysis.…”
Section: Introductionmentioning
confidence: 99%