Prenatal Diagnosis of Persistent Urogenital Sinus with Duplicated Hydrometrocolpos and Ascites – A Case Report

Abstract

We report a successful case of persistent urogenital sinus associated with a duplicated nonsyndromic form of hydrometrocolpos and ascites diagnosed prenatally. Though urogenital malformations are extremely rare and variable in presentation, the conjugation of those anomalies in a newborn is reported here for the first time. Prenatal ultrasound diagnosis was suspected at 25 weeks’ gestation and MRI imaging supported the diagnosis. Periodic ultrasound surveillance was conducted until birth at 35 weeks’ gestation by cesarean section. The presumptive diagnosis was confirmed after birth. One month later, the newborn underwent reconstructive surgical intervention with good outcome.

Urinary ascites due to persistent urogenital sinus: A case report and review of literature

“…The index case underwent vaginostomy to prevent hydronephrosis and distension of the bladder. Absence of bladder and renal anomalies is a distinct feature in our patient, similar to the case reported by Camanni et al [2], whereas all other case reports, to our knowledge had bladder and renal abnormalities as a predominant feature [3,4,[10][11][12]. We do not have clear explanation for the polyhydramnios seen only in the earlier antenatal scans.…”

Multimodal ultrasound imaging of persistent urogenital sinus with uterus didelphys and double vagina malformation

“…Clitoroplasty, urethra separation and reconstruction, vaginal pull-through, and feminization plasty were successfully performed. The infant had normal development after 19 months of follow-up [3] . But the other neonate died on postnatal day 1 and no surgical intervention was performed [4] …”

“…The infant had normal development after 19 months of follow-up. [3] But the other neonate died on postnatal day 1 and no surgical intervention was performed. [4] …”

“…Previous authors have reported 2 cases of prenatal MRI diagnosis of PUG with duplicated hydrometrocolpos, including 1 with a vaginal septum. [ 3 4 ] PUG should be identified with vaginal atresia associated with a vaginal urethral fistula.…”

“…The infant had normal development after 19 months of follow-up. [3] But the other neonate died on postnatal day 1 and no surgical intervention was performed. [4] Persistent urogenital sinus is a rare form of urogenital anomaly, with an incidence of approximately 6 in 100,000.…”