Prenatal determinants of childhood obesity: a review of risk factors

Liao, Xiang‐Peng; Yu, Yamei; Marc, Isabelle; Dubois, Lise; Abdelouahab, Nadia; Bouchard, Luigi; Wu, Yanting; Ouyang, Fengxiu; Huang, Heng-Feng; Fraser, William D.

doi:10.1139/cjpp-2018-0403

Cited by 28 publications

(24 citation statements)

References 106 publications

(111 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Additionally, mindfulness may help lifestyles of mothers by promoting better health while decreasing stress. Stress has been found to lead to gestational diabetes and endocrine function over the life course for pregnant mothers, 16,17 which could affect the health and well-being of their children. Stress management and mindful parenting can play a crucial role in lowering levels of emotional distress among children.…”

Section: Discussionmentioning

confidence: 99%

A Literature Review of the Role of Mindfulness Practices in Nutrition for Mothers and Their Children

Keaulana

Antonio

Schoch

et al. 2019

American Journal of Lifestyle Medicine

View full text Add to dashboard Cite

Nutrition-related problems have been increasingly prevalent among children and adults nationally and globally. Pregnant women and children are particularly susceptible to nutrition-related concerns. Mindfulness-based programs have demonstrated favorable outcomes for lifestyles and behaviors and may, therefore, assist in nutrition-related concerns. This column focuses on existing literature that focuses on the way mindfulness practices improve eating and nutrition outcomes for mothers. The synthesized findings of this review provide support for the effectiveness of mindfulness practices of mothers affecting improved nutrition for their children.

show abstract

Section: Discussionmentioning

confidence: 99%

A Literature Review of the Role of Mindfulness Practices in Nutrition for Mothers and Their Children

Keaulana

Antonio

Schoch

et al. 2019

American Journal of Lifestyle Medicine

View full text Add to dashboard Cite

show abstract

“…Nitrate administration from water intake [55] and toxic doses of nitrosamine compounds may also result in diabetes via generation of some free radicals but it is unclear if dietary nitrate, nitrite, or nitrosamine exposure on human T1D could act in the same manner [56]. Many perinatal risk factors which are seen in childhood diabetes are also linked with T1DM [57] like maternalchild blood group incompatibility, pre-eclampsia, neonatal infections and respiratory distress, maternal age, gestational age, birth weight and order [58][59][60][61].…”

Section: Environmental Factorsmentioning

confidence: 99%

Targeting Glycoproteins as a therapeutic strategy for diabetes mellitus and its complications

et al. 2020

View full text Add to dashboard Cite

Objectives Glycoproteins are organic compounds formed from proteins and carbohydrates, which are found in many parts of the living systems including the cell membranes. Furthermore, impaired metabolism of glycoprotein components plays the main role in the pathogenesis of diabetes mellitus. The aim of this study is to investigate the influence of glycoprotein levels in the treatment of diabetes mellitus. Methods All relevant papers in the English language were compiled by searching electronic databases, including Scopus, PubMed and Cochrane library. The keywords of glycoprotein, diabetes mellitus, glycan, glycosylation, and inhibitor were searched until January 2019. Results Glycoproteins are pivotal elements in the regulation of cell proliferation, growth, maturation and signaling pathways. Moreover, they are involved in drug binding, drug transportation, efflux of chemicals and stability of therapeutic proteins. These functions, structure, composition, linkages, biosynthesis, significance and biological effects are discussed as related to their use as a therapeutic strategy for the treatment of diabetes mellitus and its complications. Conclusions The findings revealed several chemical and natural compounds have significant beneficial effects on glycoprotein metabolism. The comprehension of glycoprotein structure and functions are very essential and inevitable to enhance the knowledge of glycoengineering for glycoprotein-based therapeutics as may be required for the treatment of diabetes mellitus and its associated complications.

show abstract

“…Lipid quality in early life may be particularly critical in individuals with an increased obesity risk due to their prenatal environment. Prenatal factors predisposing to later life obesity include maternal obesity, unbalanced diet, smoking, gestational diabetes, gestational weight gain and psychosocial stress (Liao et al, 2019). Nutritional quality of the early postnatal diet could (partially) alleviate detrimental effects of an adverse prenatal environment.…”

Section: Critical Periods In Mice and Menmentioning

confidence: 99%

Nutritional programming in early life: the role of dietary lipid quality for future health

Beek

Oosting

2020

OCL

View full text Add to dashboard Cite

Worldwide, overweight and obesity have increased dramatically, not only in high income countries. Clearly, unhealthy diets and sedentary lifestyle are important drivers of the increased obesity rates, but increasing evidence indicates that the vulnerability for later life non-communicable diseases is set during the first 1000 days, the period from conception until 2 years of age. The growth during this period is faster than during any other period in life. Dietary fats provide energy for growth, but also supply essential fatty acid (FA) precursors for long chain polyunsaturated FA that are building blocks and signals for adipose tissue development. Both epidemiological and experimental data support the notion that specific improvements in dietary fat quality, e.g. specific changes in the fatty acid composition as well as the structural organization of dietary lipids, may reduce the risk of obesity and other adverse outcomes in later life, but clinical evidence is limited and largely inconclusive. We anticipate that effects of such relatively small improvements in nutrient quality may be difficult to measure on the short term and have limited impact in healthy children. However, for children that already experience challenging conditions in the womb and have a higher risk profile based on deviations in birthweight and postnatal growth, the potential protective effects of improved dietary lipid quality in early life could be more substantial. Results from randomized clinical studies testing improved lipid quality concepts will help to develop specific strategies to adapt infant nutrition based on the need with the aim to improve long term outcomes.Keywords: LA-ALA ratio / fatty acid composition / dietary fat structure / metabolic programming / obesity risk ☆ Contribution to the Topical Issue "Lipids and health / Lipides et santé".

show abstract

Prenatal determinants of childhood obesity: a review of risk factors

Cited by 28 publications

References 106 publications

A Literature Review of the Role of Mindfulness Practices in Nutrition for Mothers and Their Children

A Literature Review of the Role of Mindfulness Practices in Nutrition for Mothers and Their Children

Targeting Glycoproteins as a therapeutic strategy for diabetes mellitus and its complications

Nutritional programming in early life: the role of dietary lipid quality for future health

Contact Info

Product

Resources

About