Preimplantation genetic screening for abnormal number of chromosomes (aneuploidies) in in vitro fertilisation or intracytoplasmic sperm injection

Sequential embryo scoring as a predictor of aneuploidy in poor-prognosis patients

“…The data presented here show that there is no advantage to aneuploidy screening when SES is employed in a routine manner. The results further support previous studies showing no significant increase in ongoing pregnancy rates using PGS (Blockeel et al, 2008;Hardarson et al, 2008;Jansen et al, 2008;Mastenbroek et al, 2007;Staessen et al, 2004Staessen et al, , 2008Twisk et al, 2006Twisk et al, , 2008. However the current data is a unique retrospective analysis in that it compares the outcomes of PGS patients that elected or qualified for a PGS option, but did not proceed with it, to outcomes when the same group did proceed with PGS.…”

Sequential embryo scoring as a predictor of aneuploidy in poor-prognosis patients

“…The data presented here show that there is no advantage to aneuploidy screening when SES is employed in a routine manner. The results further support previous studies showing no significant increase in ongoing pregnancy rates using PGS (Blockeel et al, 2008;Hardarson et al, 2008;Jansen et al, 2008;Mastenbroek et al, 2007;Staessen et al, 2004Staessen et al, , 2008Twisk et al, 2006Twisk et al, , 2008. However the current data is a unique retrospective analysis in that it compares the outcomes of PGS patients that elected or qualified for a PGS option, but did not proceed with it, to outcomes when the same group did proceed with PGS.…”

Follicular fluid protein content (FSH, LH, PG4, E2 and AMH) and polar body aneuploidy

“…a pregnancy rate of 21.12 % per transfer. This value is similar to those obtained with PGS in the same indications [37,53,60]. Our pregnancy rate may appear to be rather low but it must be borne in mind that our patients had a poor overall IVF prognosis.…”

Preimplantation genetic screening: a survey of in vitro fertilization clinics

“…12,19 There is some research supporting the use of PGS for patients experiencing recurrent IVF failure 3,20 and for IVF patients of AMA. 3,9,20 -22 However, several studies, including two that were randomized 8,12 and one meta-analysis, 7 found that PGS is not effective for women of AMA and may in fact be detrimental. 8 In the most recent and widely reported study, Mastenbroek et al 8 randomized a large number of women and measured several different endpoints, from implantation to live birth.…”

Sequential embryo scoring as a predictor of aneuploidy in poor-prognosis patients

“…The data presented here show that there is no advantage to aneuploidy screening when SES is employed in a routine manner. The results further support previous studies showing no significant increase in ongoing pregnancy rates using PGS (Blockeel et al, 2008;Hardarson et al, 2008;Jansen et al, 2008;Mastenbroek et al, 2007;Staessen et al, 2004Staessen et al, , 2008Twisk et al, 2006Twisk et al, , 2008. However the current data is a unique retrospective analysis in that it compares the outcomes of PGS patients that elected or qualified for a PGS option, but did not proceed with it, to outcomes when the same group did proceed with PGS.…”

Follicular fluid protein content (FSH, LH, PG4, E2 and AMH) and polar body aneuploidy

“…a pregnancy rate of 21.12 % per transfer. This value is similar to those obtained with PGS in the same indications [37,53,60]. Our pregnancy rate may appear to be rather low but it must be borne in mind that our patients had a poor overall IVF prognosis.…”

Preimplantation genetic screening: a survey of in vitro fertilization clinics

“…12,19 There is some research supporting the use of PGS for patients experiencing recurrent IVF failure 3,20 and for IVF patients of AMA. 3,9,20 -22 However, several studies, including two that were randomized 8,12 and one meta-analysis, 7 found that PGS is not effective for women of AMA and may in fact be detrimental. 8 In the most recent and widely reported study, Mastenbroek et al 8 randomized a large number of women and measured several different endpoints, from implantation to live birth.…”

Sequential embryo scoring as a predictor of aneuploidy in poor-prognosis patients

“…The data presented here show that there is no advantage to aneuploidy screening when SES is employed in a routine manner. The results further support previous studies showing no significant increase in ongoing pregnancy rates using PGS (Blockeel et al, 2008;Hardarson et al, 2008;Jansen et al, 2008;Mastenbroek et al, 2007;Staessen et al, 2004Staessen et al, , 2008Twisk et al, 2006Twisk et al, , 2008. However the current data is a unique retrospective analysis in that it compares the outcomes of PGS patients that elected or qualified for a PGS option, but did not proceed with it, to outcomes when the same group did proceed with PGS.…”

Follicular fluid protein content (FSH, LH, PG4, E2 and AMH) and polar body aneuploidy

“…a pregnancy rate of 21.12 % per transfer. This value is similar to those obtained with PGS in the same indications [37,53,60]. Our pregnancy rate may appear to be rather low but it must be borne in mind that our patients had a poor overall IVF prognosis.…”

Preimplantation genetic screening: a survey of in vitro fertilization clinics

“…12,19 There is some research supporting the use of PGS for patients experiencing recurrent IVF failure 3,20 and for IVF patients of AMA. 3,9,20 -22 However, several studies, including two that were randomized 8,12 and one meta-analysis, 7 found that PGS is not effective for women of AMA and may in fact be detrimental. 8 In the most recent and widely reported study, Mastenbroek et al 8 randomized a large number of women and measured several different endpoints, from implantation to live birth.…”