Pregnancy in Perinatally HIV-Infected Adolescents and Young Adults—Puerto Rico, 2002

Small for gestational age birth outcomes in pregnant women with perinatally acquired HIV

“…[32-33] However, rates of preterm birth in women with PAH in developed countries are similar to those found in our study (13.3 – 36%). [26-29] In addition, other studies reported similar trends in CD4 cell counts both before (mean initial CD4 cell count 144-314 cells/mm 3 ) [27-28] and during the pregnancy (136-394 cells/mm 3 ) [28-31, 34] in women with PAH as seen in our cohort. Reported rates of maternal virologic suppression at delivery, however, were lower in most other series [27-30] than those seen in our study.…”

Growth patterns in the first year of life differ in infants born to perinatally vs. nonperinatally HIV-infected women

“…Evidence shows that PHIV pregnant women are more immunosuppressed than their NPHIV counterparts. Several studies reported similarly low CD4 cell counts both before (mean initial CD4 cell count 144-314 cells/mm 3 ) [13, 17, 18] and during the pregnancy (136-394 cells/mm 3 ) [14, 15, 17, 18, 30, 32] in PHIV women as seen in our cohort. Our finding of decreased rates of maternal virologic suppression at delivery in PHIV women is also consistent with other reports.…”