Pregnancy and Corneal Allograft Rejection

Spontaneous corneal melting during pregnancy: a case report

“…Thus, most autoimmune diseases do not improve during pregnancy, while some autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis, have been shown to be temporarily subside [13]. Regarding the eye, autoimmune uveitis has been shown to resolve during pregnancy [14], but allograft rejection still occurs [15]. We observed marginal keratitis in the patient in the present study, but this immediately responded to topical steroids.…”

Spontaneous corneal melting during pregnancy: a case report

“…Thus, most autoimmune diseases do not improve during pregnancy, while some autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis, have been shown to be temporarily subside [13]. Regarding the eye, autoimmune uveitis has been shown to resolve during pregnancy [14], but allograft rejection still occurs [15]. We observed marginal keratitis in the patient in the present study, but this immediately responded to topical steroids.…”

Management of high-risk corneal transplantation

“…65,94,148,160 Presence of recipient lympho-cytotoxic antibodies due to a previous graft or corneal rejection, and blood transfusions may also increase risk of rejection. 98 Rejection during and after pregnancy is a common occurrence in all forms of transplantation, including corneal transplant recipients, 55 even though pregnancy is viewed as a state of relative immune suppression. On contrary, postpartum rejection episodes may be related to the reestablishment of a normal immune competence.…”

“…On contrary, postpartum rejection episodes may be related to the reestablishment of a normal immune competence. 55,101 …”

Spontaneous corneal melting during pregnancy: a case report

“…Thus, most autoimmune diseases do not improve during pregnancy, while some autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis, have been shown to be temporarily subside [13]. Regarding the eye, autoimmune uveitis has been shown to resolve during pregnancy [14], but allograft rejection still occurs [15]. We observed marginal keratitis in the patient in the present study, but this immediately responded to topical steroids.…”

Management of high-risk corneal transplantation

“…65,94,148,160 Presence of recipient lympho-cytotoxic antibodies due to a previous graft or corneal rejection, and blood transfusions may also increase risk of rejection. 98 Rejection during and after pregnancy is a common occurrence in all forms of transplantation, including corneal transplant recipients, 55 even though pregnancy is viewed as a state of relative immune suppression. On contrary, postpartum rejection episodes may be related to the reestablishment of a normal immune competence.…”

“…On contrary, postpartum rejection episodes may be related to the reestablishment of a normal immune competence. 55,101 …”

Spontaneous corneal melting during pregnancy: a case report

“…Thus, most autoimmune diseases do not improve during pregnancy, while some autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis, have been shown to be temporarily subside [13]. Regarding the eye, autoimmune uveitis has been shown to resolve during pregnancy [14], but allograft rejection still occurs [15]. We observed marginal keratitis in the patient in the present study, but this immediately responded to topical steroids.…”

Management of high-risk corneal transplantation

“…65,94,148,160 Presence of recipient lympho-cytotoxic antibodies due to a previous graft or corneal rejection, and blood transfusions may also increase risk of rejection. 98 Rejection during and after pregnancy is a common occurrence in all forms of transplantation, including corneal transplant recipients, 55 even though pregnancy is viewed as a state of relative immune suppression. On contrary, postpartum rejection episodes may be related to the reestablishment of a normal immune competence.…”

“…On contrary, postpartum rejection episodes may be related to the reestablishment of a normal immune competence. 55,101 …”