Pregnancy Among Women with Kidney Transplantation: A 20-Years Single-Center Registry

Mariano, Stephanye; Guida, José Paulo; Sousa, Marcos Vinícius de; Parpinelli, Mary Ângela; Surita, Fernanda Garanhani; Mazzali, Marilda; Costa, Maria Laura

doi:10.1055/s-0039-1688834

Cited by 10 publications

(6 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Otra de las complicaciones que se puede dar durante el embarazo de las mujeres receptoras de TR es la diabetes gestacional, siendo el riesgo de desarrollarla El Houssni S et al 27 Wyld ML et al 29 Yi-Ping L et al Cândido C et al 33 Shah S et al 35 Majak GB et al 37 menor en comparación con el resto de complicaciones 43,45 Bachmann F et al 24 Ozban M et al 26 El Houssni S et al 27 Yoshikawa Y et al 28 Wyld ML et al 29 Mariano S et al 30 Yi-Ping L et al 31 Candido C et al 32 Cândido C et al 33 Shah S et al 35 Majak GB et al 37 Normann E et al…”

Section: Discussionunclassified

“…Tanto la hipertensión arterial como la proteinuria, los niveles altos de creatinina sérica, la preeclampsia y el intervalo de tiempo desde el TR hasta el embarazo inferior a 1 año son predictores de resultados adversos en la función del injerto y en el riesgo de pérdida del mismo 23,24,30,33,35,39 .…”

Section: Los Fármacos Inmunosupresores Más Utilizados Antes Del Embar...unclassified

“…Sin embargo, en casi la totalidad de la población estudiada la función del injerto se mantiene estable durante el embarazo y el seguimiento postparto al tener controlados los factores citados anteriormente 24,30 . Además, la incidencia de rechazo agudo o pérdida del injerto es mínima, de manera que las mujeres con TR que quedan embarazadas no tienen más riesgo de fallo del injerto durante el seguimiento que las no embarazadas 22-24,27,31-33,35,39 .…”

Section: Los Fármacos Inmunosupresores Más Utilizados Antes Del Embar...unclassified

See 2 more Smart Citations

Embarazo y trasplante renal. Una revisión sistemática

et al. 2021

View full text Add to dashboard Cite

Introducción: El trasplante renal es la mejor opción como tratamiento renal sustitutivo, por sus múltiples beneficios, permitiendo además a las mujeres con enfermedad renal crónica la posibilidad de embarazo y de una gestación exitosa.Objetivo: Conocer y sintetizar la producción científica más actualizada sobre el embarazo en mujeres con trasplante renal.Metodología: Se realizó una revisión sistemática siguiendo las recomendaciones de la declaración PRISMA, en las bases de datos PubMed, ProQuest, Scielo y Scopus. La estrategia de búsqueda se estableció con los siguientes descriptores: “pregnancy” y “kidney transplantation”. Se incluyeron artículos originales y revisiones sistemáticas, en español e inglés publicados entre 2015 y 2020.Resultados: Se seleccionaron 18 artículos. Se encontró una edad media de las mujeres trasplantadas en el momento del parto entre los 30 y 34 años y un tiempo medio entre el trasplante renal y el embarazo de 4,2 años. Las complicaciones más frecuentes en la madre fueron la preeclampsia, la hipertensión arterial inducida por el embarazo y la infección del tracto urinario, así como un aumento de la creatinina sérica y proteinuria. La mayoría de los embarazos terminaron en cesáreas y, entre los nacidos vivos, existió un gran número de prematuros.Conclusiones: El embarazo en mujeres con trasplante renal resulta exitoso siempre que la función renal se mantenga estable y no aparezcan complicaciones. Las complicaciones más frecuentes durante el embarazo son la hipertensión y la preeclampsia. La complicación más frecuente en el neonato es la prematuridad.

show abstract

Section: Discussionunclassified

Section: Los Fármacos Inmunosupresores Más Utilizados Antes Del Embar...unclassified

See 1 more Smart Citation

Embarazo y trasplante renal. Una revisión sistemática

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Interactions of these drugs with anesthetic drugs are also important. For example, as a result of azathioprine use, bone marrow suppression may occur and cause leukopenia or thrombocytopenia [8][9][10][11]. The other side effects of azathioprine include gastrointestinal intolerance, liver function abnormalities, and infections.…”

Section: Discussionmentioning

confidence: 99%

Retrospective Evaluation of Anesthetic Techniques in Pregnant Women With Renal Transplantation

Sargın¹,

Karaman²,

Ari³

et al. 2019

Turk J Med Sci

View full text Add to dashboard Cite

Introduction Menstrual cycle disorders and amenorrhea are common problems in women with chronic renal failure. The reason is the suppression of gonadotropin-releasing hormone (GnRH) secretion due to uremia, and hypothalamopituitary dysfunction. Especially with new and advanced treatment protocols, the rate of conception is now 0.5%-7% among patients with end stage renal failure. As a result of the increase in the success rate of renal transplantations, renal and endocrine functions are rapidly restored in these patients and ovulatory cycles occur. Although a successful conception is achieved after renal transplantation, numerous maternal and fetal risks may arise. It is important to keep the immunosuppressive drug doses used after renal transplantation in pregnant women who underwent renal transplantation at a proper level in terms of both maintaining the graft function and protecting the health of the mother and fetus. While the number of abortions is quite high in these patient groups, prematurity and intrauterine growth restriction (IUGR) commonly Background/aim: The aim of this study was to evaluate anesthesia management in cesarean operation of pregnant women who underwent renal transplantation and the effects on postoperative renal function, retrospectively. Materials and methods: After obtaining the approval of the ethics committee of our hospital, the records of pregnant women who underwent kidney transplantation and cesarean section between 2007 and 2017 were retrospectively analyzed. The patients' demographic data, concomitant disease history, the treatment received, and type of anesthesia were retrospectively evaluated and recorded in the follow-up form. Results: It was found that a total of 47 women who underwent renal transplantation had 47 live births by cesarean section. The mean age of the pregnant women was 30 ± 5.34 years. The mean time between renal transplantation and conception was 95.34 ± 55.02 months. It was found that 14 (29%) of a total of 47 patients had their first pregnancy. The number of patients with a gravidity of 4 and above was 9 (19%). A total of 21 (44.7%) pregnant women had spontaneous miscarriage. Five (10.6%) patients were treated with curettage for therapeutic purposes. Twenty-two (46%) of the patients whose immunosuppressive therapy was continuing were treated with azathioprine, tacrolimus, and prednisolone. The mean gestational age of delivery was 36.5 ± 1.59 weeks. The rate of prepregnancy hypertension diagnosis was 25.5% (n = 12), while the rate of developing gestational hypertension was 21.3% (n = 10). Spinal anesthesia was administered to 42 (91%) of 47 patients who underwent cesarean section. In the preoperative period, the mean value of serum blood urea nitrogen was 62.88 ± 41.97 mg/dL and the mean serum creatinine level was 3.21 ± 6.17 mg/dL. In the postoperative period, these values were 44.4 ± 29.9 mg/dL and 1.91 ± 1.63 mg/dL, respectively. When the pre-and postoperative serum urea and creatinine levels were compared, they were found to be lower in the postoperati...

show abstract

“…Among postpartum women, 82% received some postpartum contraception, with tubal ligation performed in 1/3 of cases. 6 Liver Liver diseases of any etiology are always a challenge for monitoring pregnancy, as situations of extreme severity in obstetrics, such as HELLP syndrome and fatty liver of pregnancy cholestasis, can overlap with the underlying disease, making diagnosis and therapeutic approach difficult and increase maternal risks. In LTx, it is no different, as the situations described above can occur and must be differentiated from graft rejection episodes.…”

Section: Kidneymentioning

confidence: 99%

Pregnancy and Reproductive Planning in Transplanted Women

Surita,

Guida,

Juliato

et al. 2023

BJT

View full text Add to dashboard Cite

The objective of this literature review is to provide some pregnancy results in transplanted women, proposals for preconception, prenatal and postpartum evaluation, including postpartum contraception, and therapeutic guidance during pregnancy and lactation. Based on the results found in research on PubMed without date or language limitations, we discuss the importance of reproductive planning for women with solid organ transplants and what should be done before the transplant. There are formal contraindications to pregnancy; however, when planned, within clinical and laboratory criteria, and with adequate immunosuppression and specialized prenatal care, pregnancy is possible with good perinatal results. We also highlight the importance of psychological support among pregnant women with solid organ transplants.

show abstract

Pregnancy Among Women with Kidney Transplantation: A 20-Years Single-Center Registry

Cited by 10 publications

References 20 publications

Embarazo y trasplante renal. Una revisión sistemática

Embarazo y trasplante renal. Una revisión sistemática

Retrospective Evaluation of Anesthetic Techniques in Pregnant Women With Renal Transplantation

Pregnancy and Reproductive Planning in Transplanted Women

Contact Info

Product

Resources

About