Prefrontal contributions to domain-general executive control processes during temporal context retrieval

Rajah, M. Natasha; Ames, Blaine; D’Esposito, Mark

doi:10.1016/j.neuropsychologia.2007.10.023

Cited by 57 publications

(42 citation statements)

References 71 publications

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“…Alternatively, task difficulty could be related to memory strength, resulting in longer RTs for items poorly encoded. RT is often used as a marker of task difficulty and it has been employed to examine difficulty in categorization of items (Taylor & Thoroughman, 2008;Rajah, Ames, & DʼEsposito, 2007;West & Holcomb, 2002;Demb et al, 1995;Kounios & Holcomb, 1994). In the present study when activation was examined in relation to RT, differing levels of activation in DLPFC and in the anterior hippocampus were observed.…”

Section: Task Difficulty and The Default Networkmentioning

confidence: 56%

Going Their Separate Ways: Dissociation of Hippocampal and Dorsolateral Prefrontal Activation during Episodic Retrieval and Post-retrieval Processing

Israel

Seibert²,

Black³

et al. 2010

Journal of Cognitive Neuroscience

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Hippocampal activity is modulated during episodic memory retrieval. Most consistently, a relative increase in activity during confident retrieval is observed. Dorsolateral prefrontal cortex (DLPFC) is also activated during retrieval, but may be more generally activated during cognitive-control processes. The "default network," regions activated during rest or internally focused tasks, includes the hippocampus, but not DLPFC. Therefore, DLPFC and the hippocampus should diverge during difficult tasks suppressing the default network. It is unclear, however, whether a difficult episodic memory retrieval task would suppress the default network due to difficulty or activate it due to internally directed attention. We hypothesized that a task requiring episodic retrieval followed by rumination on the retrieved item would increase DLPFC activity, but paradoxically reduce hippocampal activity due to concomitant suppression of the default network. In the present study, blocked and event-related fMRI were used to examine hippocampal activity during episodic memory recollection and postretrieval processing of paired associates. Subjects were asked to make living/nonliving judgments about items visually presented (classify) or items retrieved from memory (recall-classify). Active and passive baselines were used to differentiate task-related activity from default-network activity. During the "recall-classify" task, anterior hippocampal activity was selectively reduced relative to "classify" and baseline tasks, and this activity was inversely correlated with DLPFC. Reaction time was positively correlated with DLPFC activation and default-network/hippocampal suppression. The findings demonstrate that frontal and hippocampal activity are dissociated during difficult episodic retrieval tasks and reveal important considerations for interpreting hippocampal activity associated with successful episodic retrieval.

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Section: Task Difficulty and The Default Networkmentioning

confidence: 56%

Going Their Separate Ways: Dissociation of Hippocampal and Dorsolateral Prefrontal Activation during Episodic Retrieval and Post-retrieval Processing

Israel

Seibert²,

Black³

et al. 2010

Journal of Cognitive Neuroscience

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“…Although we cannot determine from our current experimental design, prior studies of the specific cognitive processes mediated by distinct nodes of activity, such as left DLPFC, have emphasized the role of left DLPFC during successful context retrieval (Thaiss and Petrides, 2003;Dobbins et al, 2004;Mitchell et al, 2004Mitchell et al, , 2006, and have suggested that this region is involved in mediating cognitive control processes during memory retrieval, such as retrieval search, response selection, and/or postretrieval monitoring (Rajah et al, 2008). Similarly, several studies have reported greater inferior parietal cortex activity during retrieval success (Wagner et al, 2005).…”

Section: Age-related Changes In Right More Than Left Mfg Volumementioning

confidence: 88%

“…The stimuli have been used in several context memory tasks in the laboratory (Rajah et al, 2008(Rajah et al, , 2010, and details about the stimuli can be found in Rajah et al (2008Rajah et al ( , 2010. The set of stimuli used for each memory task was balanced for age, gender, and neutral/pleasantness rating.…”

Section: Behavioral Methodsmentioning

confidence: 99%

“…In young adults, context retrieval has been associated with bilateral MFG activity, and there is debate as to which cognitive processes left versus right MFG mediates during context retrieval (Dobbins et al, 2003;Knoch et al, 2006;Slotnick and Moo, 2006;Hayama and Rugg, 2009;Kaller et al, 2011). Our recent studies suggest that left and right MFG may mediate response selection and monitoring processes, respectively, during context retrieval (Rajah et al, 2008(Rajah et al, , 2010.…”

Section: Introductionmentioning

confidence: 93%

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Age-Related Changes in Right Middle Frontal Gyrus Volume Correlate with Altered Episodic Retrieval Activity

Rajah¹,

Languay²,

Grady³

2011

J. Neurosci.

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Age-related deficits in episodic retrieval have been associated with volume reductions in the middle frontal gyrus (MFG). However, it remains unclear how this age-related reduction in MFG volume correlates with neural activity during retrieval. To address this, we conducted in vivo volumetry of the frontal cortex in young and older human adults and found more volume loss on the right than on the left MFG with age. We then examined how left and right MFG volume correlated with fMRI activity during successful retrieval of item, spatial context, and temporal context information in both age groups. In young adults, larger right MFG volume was positively correlated with greater activity in a commonly found episodic retrieval network that included bilateral dorsolateral prefrontal cortex (DLPFC) and bilateral inferior parietal cortex. Within this network, left DLPFC and right inferior parietal cortex activity predicted memory performance. In older adults, a positive structure-function association in DLPFC for either left or right MFG/DLPFC was not observed. Instead, right MFG volume was negatively correlated with activity in several regions in older adults, including the parahippocampal cortex (PHC) and anterior cingulate. Less activity in the PHC region predicted better item memory, and less activity in the anterior cingulate predicted better spatial context accuracy in older adults. We conclude that age-related change in the structure-function association in MFG/DLPFC impacts retrieval activity and performance, and those older adults with larger right MFG volume attempt to compensate for this change by modifying activity in other brain regions to help retrieval performance.

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“…They found that bilateral DLPFC and frontopolar activity increased with the number of subprocesses required to make the test decision, but not with the level of supporting evidence in memory (also see Hayama, Johnson, & Rugg, 2008;Rajah, Ames, & DʼEsposito, 2008). The exact nature of the decision rules used in these tasks as well as the degree that they may have relied on recollection and familiarity is unclear.…”

Section: Introductionmentioning

confidence: 99%

Dissociating Source Memory Decisions in the Prefrontal Cortex: fMRI of Diagnostic and Disqualifying Monitoring

Gallo

McDonough

Scimeca

2010

Journal of Cognitive Neuroscience

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We used event-related fMRI to study two types of retrieval monitoring that regulate episodic memory accuracy: diagnostic and disqualifying monitoring. Diagnostic monitoring relies on expectations, whereby the failure to retrieve expected recollections prevents source memory misattributions (sometimes called the distinctiveness heuristic). Disqualifying monitoring relies on corroborative evidence, whereby the successful recollection of accurate source information prevents misattribution to an alternative source (sometimes called recall to reject). Using criterial recollection tests, we found that orienting retrieval toward distinctive recollections (colored pictures) reduced source memory misattributions compared with a control test in which retrieval was oriented toward less distinctive recollections (colored font). However, the corresponding neural activity depended on the type of monitoring engaged on these tests. Rejecting items based on the absence of picture recollections (i.e., the distinctiveness heuristic) decreased activity in dorsolateral prefrontal cortex relative to the control test, whereas rejecting items based on successful picture recollections (i.e., a recall-to-reject strategy) increased activity in dorsolateral prefrontal cortex. There also was some evidence that these effects were differentially lateralized. This study provides the first neuroimaging comparison of these two recollection-based monitoring processes and advances theories of prefrontal involvement in memory retrieval.

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Prefrontal contributions to domain-general executive control processes during temporal context retrieval

Cited by 57 publications

References 71 publications

Going Their Separate Ways: Dissociation of Hippocampal and Dorsolateral Prefrontal Activation during Episodic Retrieval and Post-retrieval Processing

Going Their Separate Ways: Dissociation of Hippocampal and Dorsolateral Prefrontal Activation during Episodic Retrieval and Post-retrieval Processing

Age-Related Changes in Right Middle Frontal Gyrus Volume Correlate with Altered Episodic Retrieval Activity

Dissociating Source Memory Decisions in the Prefrontal Cortex: fMRI of Diagnostic and Disqualifying Monitoring

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