Predictors of Dropout in Exercise Trials in Older Adults: The Generation 100 Study

Viken, Hallgeir; Reitlo, Line Skarsem; Zisko, Nina; Nauman, Javaid; Aspvik, Nils Petter; Ingebrigtsen, Jan Erik; Wisløff, Ulrik; Stensvold, Dorthe

doi:10.1249/mss.0000000000001742

Cited by 21 publications

(19 citation statements)

References 24 publications

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“…The low physical functioning and low SE of the subjects were the reasons for the high dropout rate. It has been shown that physical function, exercise habits, and exercise tolerance influenced the physical health of the community residents in the dropout group when compared with the continuous exercise group 42 . The present study included individuals with an SPPB ≤ 9, and it is plausible that low physical function and low SE might have affected the dropouts.…”

Section: Discussionmentioning

confidence: 86%

Effects of exercise therapy on the persistence of physical function, exercise habits, and self‐efficacy after cessation of exercise in patients undergoing hemodialysis: A nonrandomized control trial

Yamaguchi¹,

Yabe

Mitake

et al. 2021

Ther Apher Dial

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The present study investigated the sustained effect of exercise therapy discontinuation in patients under hemodialysis with low physical function. Seven subjects in the exercise group and eight in the control group who had low physical function (short physical performance battery; SPPB ≤ 9 points) were included in the study. The exercise group received 6 months of intradialytic exercise, followed by 6 months of observation. We assessed SPPB, grip strength, self‐efficacy (SE), and exercise habits in both the groups before and after 12 months. There were statistically significant improvements in SPPB (effect size, 0.58; 95% confidence interval [CI], 0.13–3.55) and SE (effect size, 0.59; 95% CI, 0.25–7.57) in the exercise group relative to the control group. The exercise group displayed more exercise habits than the control group at 12 months. A 6‐month period of intradialytic exercise may contribute to the continuation of SPPB and SE after exercise discontinuation.

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Section: Discussionmentioning

confidence: 86%

Effects of exercise therapy on the persistence of physical function, exercise habits, and self‐efficacy after cessation of exercise in patients undergoing hemodialysis: A nonrandomized control trial

Yamaguchi¹,

Yabe

Mitake

et al. 2021

Ther Apher Dial

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“…In this study, we observed a significant difference in age between the continuation and dropout groups. Increasing age has commonly been reported as a predictor of adherence within the literature [21,33]. However, no significant differences were noted in SPPB scores, rate of weight gain, exercise habits, exercise intervention between the groups.…”

Section: Discussionmentioning

confidence: 76%

“…In a previous study, 36.8% of patients assessed once or twice per year continuously participated in a similar program [9]. In another study, dropout rates from exercise therapy among older adults were 11.0% and 14.9% at 1 and 3 years, respectively [21]. Previous studies have also reported dropout rates of 27.0% and 32.0% among patients with type 2 [22] diabetes and patients undergoing HD on non-dialysis days at home [23], respectively.…”

Section: Discussionmentioning

confidence: 95%

“…This weight management factor may explain the lack of difference in the rate of weight gain between the groups during dialysis. Previous studies have reported that the rate of habitual exercise is 74.9% among older adults in the general population [21], 52.3% among patients with diabetes [35], and 64.0% among patients with chronic kidney disease [36]. In a previous study of older adults living in the community [21], the presence or absence of exercise habit was extracted as a factor associated with program dropout.…”

Section: Discussionmentioning

confidence: 99%

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Factors associated with dropout from physical function assessment programs among participants receiving maintenance hemodialysis: A retrospective observational cohort study

Yamaguchi¹,

Yabe

Mitake

et al. 2021

Ther Apher Dial

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We aimed to investigate the factors associated with dropout from a physical function assessment program among participants receiving outpatient hemodialysis (HD). The participants were divided into continuation and dropout groups and followed up for 3 years after the initial physical function assessment. Multivariate logistic regression analyses were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for the dropout group to determine the factors associated with dropout from the physical function assessment program. The continuation and dropout groups included 43 and 58 participants, respectively. The continuation group had a significantly higher self-efficacy (SE) and age than the dropout group (p = 0.001, p = 0.047). Multivariate logistic regression analysis indicated that only SE (OR: 1.202, 95% CI:1.082-1.334) remained a significant predictor after adjustment (p < 0.05). There is a need to evaluate SE to prevent dropout from physical functioning assessment programs.

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“…3 However, the rates of dropout from exercise programs are higher in people with lower levels of physical activity and muscle strength. 29 These previous studies suggest the difficulty of applying physical activity interventions to the prevention of sarcopenia. The present study results showed that coffee is associated with SMI independent of physical activity measured by accelerometers.…”

Section: Discussionmentioning

confidence: 99%

Association between habitual coffee consumption and skeletal muscle mass in middle‐aged and older Japanese people

Iwasaka

Yamada

Nishida

et al. 2021

Geriatrics Gerontology Int

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Aims: Coffee consumption has been suggested, in animal studies, to inhibit the progression of sarcopenia, possibly through its anti-inflammatory effects; however, few studies have been carried out in humans. We aimed to examine whether coffee consumption was related to indicators of sarcopenia in a Japanese population, and whether the association was mediated by reduced inflammation.Methods: This study was a cross-sectional design. Participants were community residents (n = 6369) aged 45-74 years. We measured skeletal muscle mass index (SMI; kg/m 2 ) by a bioelectrical impedance method, and grip strength with a Smedley-type dynamometer. Habitual coffee consumption was assessed by a self-administered questionnaire. Serum high-sensitivity C-reactive protein was measured as an inflammatory marker. The association between habitual coffee consumption and SMI or grip strength was analyzed with a linear regression model adjusted for covariates.Results: A significant positive association was found between coffee consumption and SMI (men: β = 0.023; P trend = 0.004, women: β = 0.011; P trend = 0.012). Further adjustment for high-sensitivity C-reactive protein did not materially alter the results (men: β = 0.023; P trend = 0.005, women: β = 0.009; P trend = 0.024). The relationship between coffee consumption and grip strength did not reach statistical significance; however, a positive trend was observed (men: β = 0.208; P trend = 0.085, women: β = 0.092; P trend = 0.167). Conclusions:We found that coffee consumption was positively associated with SMI independently of inflammation in middle-aged and older Japanese people. Reduced inflammation by coffee does not seem to be an important mediator, and further investigations are required to explore the mechanisms of this association.

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Predictors of Dropout in Exercise Trials in Older Adults: The Generation 100 Study

Abstract: This is the largest study to identify dropout-predictors in a long-term exercise program in older adults. Our findings provide new and important knowledge about potential risk factors of dropout in long-term exercise programs in older adults.

Cited by 21 publications

References 24 publications

Effects of exercise therapy on the persistence of physical function, exercise habits, and self‐efficacy after cessation of exercise in patients undergoing hemodialysis: A nonrandomized control trial

Effects of exercise therapy on the persistence of physical function, exercise habits, and self‐efficacy after cessation of exercise in patients undergoing hemodialysis: A nonrandomized control trial

Factors associated with dropout from physical function assessment programs among participants receiving maintenance hemodialysis: A retrospective observational cohort study

Association between habitual coffee consumption and skeletal muscle mass in middle‐aged and older Japanese people

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