Predictors of Asthma Control by Stepwise Treatment in Elderly Asthmatic Patients

Ban, Ga Young; Ye, Young-Min; Lee, Yunhwan; Kim, Jeong Eun; Nam, Young Hee; Lee, Soo Keol; Kim, Joo Hee; Jung, Ji Ye; Kim, Sang-Ha; Park, Hae‐Sim

doi:10.3346/jkms.2015.30.8.1042

Cited by 21 publications

(12 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Six publications found strong and consistent correlations between improvement in ACT score and improvement in ACQ score [8][9][10][11][12][13], with five of the publications assessing the statistical significance of the correlations. All five of these reports found statistically significant Number of asthma exacerbations 10 2 26,27 (2) 26,27 8 17,22,23,28-32 (7) 22,23,[28][29][30][31][32] Lung function 17 8 3,15,27,33-37 (5 b ) 3,34-37 9 11,13,18,38-43 (7 b ) 11,13,[38][39][40]42,43 General HRQoL 7 0 (0) 7 [49][50][51][52][53][54][55] (5 b ) 49,50,[52][53][54] Asthma-related QoL 7 5 28,34,[44][45][46] (5) 28,34,44-46 2 47,48 (2) 47,48 Sleep quality 6 2 45,56 (2) 45,56 5 [56][57]…”

Section: Act Score and Asthma Symptom Controlmentioning

confidence: 96%

See 1 more Smart Citation

Relationship between the Asthma Control Test (ACT) and other outcomes: a targeted literature review

et al. 2020

View full text Add to dashboard Cite

Background: The Asthma Control Test (ACT) has been used to assess asthma control in both clinical trials and clinical practice. However, the relationships between ACT score and other measures of asthma impact are not fully understood. Here, we evaluate how ACT scores relate to other clinical, patient-reported, or economic asthma outcomes. Methods: A targeted literature search of online databases and conference abstracts was performed. Data were extracted from articles reporting ACT score alongside one or more of: Asthma Control Questionnaire (ACQ) score; rescue medication use; exacerbations; lung function; health−/asthma-related quality of life (QoL); sleep quality; work and productivity; and healthcare resource use (HRU) and costs. Results: A total of 1653 publications were identified, 74 of which were included in the final analysis. Of these, 69 studies found that improvement in ACT score was related to improvement in outcome(s), either as correlation or by association. The level of evidence for each relationship differed widely between outcomes: substantial evidence was identified for relationships between ACT score and ACQ score, lung function, and asthma-related QoL; moderate evidence was obtained for relationships between ACT score and rescue medication use, exacerbations, sleep quality, and work and productivity; limited evidence was identified for relationships between ACT score and general health-related QoL, HRU, and healthcare costs. Conclusions: Findings of this review suggest that the ACT is an appropriate measure for overall asthma impact and support its use in clinical trial settings. GlaxoSmithKline plc. study number HO-17-18170.

show abstract

Section: Act Score and Asthma Symptom Controlmentioning

confidence: 96%

“…Ten studies reported on the relationship between improvement in ACT score and reduction in asthma exacerbations (Table 1) [17,22,23,[26][27][28][29][30][31][32].…”

Section: Act Score and Asthma Exacerbationsmentioning

confidence: 99%

Relationship between the Asthma Control Test (ACT) and other outcomes: a targeted literature review

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Many questions remain unanswered in elderly patients, as this population is partially excluded from randomized clinical trials due to age criteria and comorbidities. A recent study examined the predicators of asthma control in elderly patients with asthma in South Korea 5253. This study showed that the number of medications for comorbidities, as well as functional status, determined by the higher physical functioning scale, are important parameters in assessing and predicting asthma control 53.…”

Section: Treatment Optionsmentioning

confidence: 99%

“…A recent study examined the predicators of asthma control in elderly patients with asthma in South Korea 5253. This study showed that the number of medications for comorbidities, as well as functional status, determined by the higher physical functioning scale, are important parameters in assessing and predicting asthma control 53. A large number of medications were associated with unfavorable outcomes, and it is recommended that treatment regimens for the elderly should be as simple as possible for elderly asthmatic patients.…”

Section: Treatment Optionsmentioning

confidence: 99%

Positioning of Long-Acting Muscarinic Antagonists in the Management of Asthma

Aalbers

Park

2017

Allergy Asthma Immunol Res

Self Cite

View full text Add to dashboard Cite

Despite a range of efficacious therapies for asthma, including inhaled corticosteroids (ICS) and long-acting β2-agonists (LABA), a significant proportion of patients have poor asthma control and retain a risk of future worsening of their symptoms. Long-acting muscarinic antagonist (LAMA) bronchodilators offer a well-tolerated, efficacious, and cost-effective add-on to a patient's treatment. Of the LAMAs currently under investigation or available for the treatment of asthma, evidence from a comprehensive clinical trial program in adults and children shows that once-daily treatment with tiotropium provides benefits for patients with uncontrolled asthma despite the use of ICS and LABAs. Tiotropium is included in the Global Initiative for Asthma (GINA) strategy document as an add-on therapy option for patients at Step 4 or 5 with a history of asthma exacerbations. Tiotropium Respimat® has demonstrated safety and efficacy in patients with a range of disease severities, ages, and phenotypes. This review describes the evidence for the use of LAMA as add-on therapy for patients with asthma who remain uncontrolled despite the use of ICS and LABA treatments.

show abstract

“…Poor asthma control is associated with increased risk of exacerbations, debilitation, impaired quality of life, increased healthcare utilization and reduced productivity [10,11,17]. The degree of asthma control appears to have a significant impact on health-related quality of life [7].…”

Section: Introductionmentioning

confidence: 99%

Development and Implementation of an Evidence-based Self-regulation Intervention: Effect on Knowledge and Perceived Control Among Adult Patients with Asthma

Bayoumy¹,

Osman²

2015

Int J Nurs Clin Pract

View full text Add to dashboard Cite

Background: Most chronic diseases are variable and an individual must exercise a significant degree of judgment regarding management. Self management therefore requires that the person understands the illness and actively participate in the treatment process. According to self regulation (SR) theory, individuals are required to set personally important goals that guide their behaviors through goalguidance process. Since, very few or almost no available data to assess self-regulation interventions focused on improving asthma knowledge and control, the current study aimed at evaluating the efficacy of asthma-self-regulation intervention among targeted patients. Methods/Design: A pre/post-test study design was used to compare a six-session asthma-self regulation intervention on participants' outcome. Intervention program was based on the principles of self-regulation for disease management, and all program activities and materials are designed to be responsive to the specific needs of participants. Thirty asthmatic patients were recruited for the study.Researchers assessed the effect of the intervention on patients' knowledge gains and control of asthma symptoms. Data were collected at baseline, immediately and two months after the program. Keywords:Asthma, Chronic disease self management, Selfregulation, Knowledge, Asthma control Research Article Open Access IntroductionAsthma is a major public health problem and one of the most common chronic conditions in the world. According to the Global Burden of Disease Study, asthma caused more than 345,000 deaths worldwide in 2010 [1]. In Europe alone, asthma affects 30 million people and the cost of asthma care in Europe is estimated at £18 billion per year; lost productivity accounts for almost £10 billion of this [1]. The second half of the 20 th century was marked by a disturbing increase in frequency of allergic diseases, affecting approximately 20 percent of the global population, and the rate of bronchial asthma amongst adults is 5.4 percent (4.9% in men and 5.8% in women) [2]. Epidemiological studies in Saudi Arabia revealed an increasing prevalence of asthma in the past three decades, which may be attributed to the rapid lifestyle changes related to the modernization of Saudi society, changes in dietary habits, and exposure to environmental factors such as indoor allergens, dust, sand storms, and tobacco [3]. Asthma, a common chronic disorder of the airways in Saudi Arabia affecting more than 2 million Saudis, ranks19 th in terms of disability-adjusted life years [4].Asthma had an enormous impact on patient's wellbeing [5], despite the availability of effective treatments and evidencebased management guidelines [6]. Asthma can result in physical, emotional, and social limitations that can impair patients' quality oflife [7]. There is a growing burden of asthma in terms of morbidity,

show abstract

Predictors of Asthma Control by Stepwise Treatment in Elderly Asthmatic Patients

Cited by 21 publications

References 25 publications

Relationship between the Asthma Control Test (ACT) and other outcomes: a targeted literature review

Relationship between the Asthma Control Test (ACT) and other outcomes: a targeted literature review

Positioning of Long-Acting Muscarinic Antagonists in the Management of Asthma

Development and Implementation of an Evidence-based Self-regulation Intervention: Effect on Knowledge and Perceived Control Among Adult Patients with Asthma

Contact Info

Product

Resources

About