2015
DOI: 10.4269/ajtmh.15-0467
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Abstract: Abstract. World Health Organization recommendations for the timing and target population for mass drug administration (MDA) for schistosomiasis are based on the prevalence of infection in school children within a given community. In a large study comparing MDA approaches for Schistosoma mansoni control, we evaluated whether prevalence of infection and egg burdens in 9-to 12-year-old students reflected infection levels in young children and adults in the same community. Cross-sectional surveys of preadolescents… Show more

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Cited by 13 publications
(14 citation statements)
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“…We investigated the relationship between currently available data on SAC and PSAC within the same community to determine if data from SAC, who are the current target of control programmes could be used to predict infection levels in PSAC. Previous studies have investigated using SAC as a proxy group for community-wide prevalence levels, showing that SAC prevalence is closely related to adult prevalence, and therefore this age group could be used as a proxy group [24,25]. Our findings confirm that this approach PLOS NEGLECTED TROPICAL DISEASES can be extended to quantify infection levels in PSAC.…”
Section: Discussionsupporting
confidence: 81%
“…We investigated the relationship between currently available data on SAC and PSAC within the same community to determine if data from SAC, who are the current target of control programmes could be used to predict infection levels in PSAC. Previous studies have investigated using SAC as a proxy group for community-wide prevalence levels, showing that SAC prevalence is closely related to adult prevalence, and therefore this age group could be used as a proxy group [24,25]. Our findings confirm that this approach PLOS NEGLECTED TROPICAL DISEASES can be extended to quantify infection levels in PSAC.…”
Section: Discussionsupporting
confidence: 81%
“…Monitoring of control program progress, like mapping, has traditionally been performed by measuring egg prevalence and the intensity of schistosome infections in school age children because they provide a useful barometer of the level of infection in other age groups in the community 44 . This age group also tends to have the highest intensities of infection, so decreases in their egg output would result in fewer eggs that could contaminate fresh water and infect snails.…”
Section: Adapting Programs As They Progressmentioning
confidence: 99%
“…There is a paucity of information on schistosomiasis prevalence levels in Kenyan adults. However, recent studies in Western Kenya suggest that prevalence in 9–12 year olds, is an excellent predictor of the prevalence in adults [6]. Thus, schistosomiasis is an ongoing community level public health problem in western Kenya.…”
Section: Introductionmentioning
confidence: 99%