Predictive Factors for Insufficient Weight Loss After Bariatric Surgery: Does Obstructive Sleep Apnea Influence Weight Loss?

Raaff, Christel A.L. de; Coblijn, Usha K.; Vries, Nico de; Heymans, Martijn W.; Berg, Bob; Tets, Willem F. van; Wagensveld, Bart A. van

doi:10.1007/s11695-015-1830-4

Cited by 33 publications

(14 citation statements)

References 19 publications

(24 reference statements)

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“…9 Finally, in a sample of 816 bariatric surgery patients, de Raaff and colleagues found that those with OSA at preoperative screening experienced less weight loss at 6 and 12 months following surgery compared to those without OSA, though the strength of the relationship weakened considerably once confounders such as age and baseline BMI were considered. 23 As we found an approximately 2% difference in weight loss between those with and without OSA in a predominantly female sample with mild OSA, our results are in agreement with prior behavioral weight loss interventions and indicate that even mild OSA may impair behavioral weight loss outcomes.…”

Section: Discussionsupporting

confidence: 87%

Bidirectional Relationships Between Weight Change and Sleep Apnea in a Behavioral Weight Loss Intervention

Kline

Burke

Sereika

et al. 2018

Mayo Clinic Proceedings

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Behaviorally induced weight loss in overweight/obese adults was associated with significant AHI reduction. However, the presence of OSA was associated with blunted weight loss, potentially via reduced adherence to behaviors supporting weight loss. These results suggest that OSA screening before attempting weight loss may be helpful to identify who may benefit from additional behavioral counseling.

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Section: Discussionsupporting

confidence: 87%

Bidirectional Relationships Between Weight Change and Sleep Apnea in a Behavioral Weight Loss Intervention

Kline

Burke

Sereika

et al. 2018

Mayo Clinic Proceedings

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“…Similarly, the number of comorbidities and previous history of hypertension predicted IWL [36]. Likewise, patients with obstructive sleep apnea achieved significantly lower EWL% at 1 year after surgery than patients with no sleep apnea [86].…”

Section: Preoperative Predictors Of Wr and Iwl Post-bsmentioning

confidence: 89%

“…The presence of comorbidities predicts WR and IWL. For instance, T2D predicted WR and IWL [34,[79][80][81]86]; while hypertension and low HDL cholesterol were both associated with poor weight trajectory [34]. Similarly, the number of comorbidities and previous history of hypertension predicted IWL [36].…”

Section: Preoperative Predictors Of Wr and Iwl Post-bsmentioning

confidence: 99%

Weight Regain and Insufficient Weight Loss After Bariatric Surgery: Definitions, Prevalence, Mechanisms, Predictors, Prevention and Management Strategies, and Knowledge Gaps—a Scoping Review

2021

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Some patients experience weight regain (WR) or insufficient weight loss (IWL) after bariatric surgery (BS). We undertook a scoping review of WR and IWL after BS. We searched electronic databases for studies addressing the definitions, prevalence, mechanisms, clinical significance, preoperative predictors, and preventive and treatment approaches including behavioral, pharmacological, and surgical management strategies of WR and IWL. Many definitions exist for WR, less so for IWL, resulting in inconsistencies in the reported prevalence of these two conditions. Mechanisms and preoperative predictors contributing to WR are complex and multifactorial. A range of the current knowledge gaps are identified and questions that need to be addressed are outlined. Therefore, there is an urgent need to address these knowledge gaps for a better evidence base that would guide patient counseling, selection, and lead to improved outcomes.

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“…Recent studies associate bariatric surgery with a considerable long-term insufficient weight loss or complications, with a secondary procedure needed in approximately 20% of patients [3,4]. The initial BMI is a significant predictive factor of insufficient weight loss, with worse weight loss results in patients with a higher initial BMI [5,6]. The treatment of people with severe obesity and BMI > 50 kg/m 2 is challenging for three main reasons: (1) insufficient weight loss is more frequent after bariatric surgery in this setting; (2) surgery is technically more demanding; and (3) surgery is associated with higher postoperative morbi-mortality [7].…”

Section: Introductionmentioning

confidence: 99%

Is One Anastomosis Gastric Bypass with a Biliopancreatic Limb of 150 cm Effective in the Treatment of People with Severe Obesity with BMI > 50?

et al. 2021

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Purpose The treatment of people with severe obesity and BMI > 50 kg/m2 is challenging. The present study aims to evaluate the short and mid-term outcomes of one anastomosis gastric bypass (OAGB) with a biliopancreatic limb of 150 cm as a primary bariatric procedure to treat those people in a referral center for bariatric surgery. Material and Methods Data of patients who underwent OAGB for severe obesity with BMI > 50 kg/m2 between 2010 and 2017 were collected prospectively and analyzed retrospectively. Follow-up comprised clinical and biochemical assessment at 1, 3, 6, 12, 18, and 24 months postoperatively, and once a year thereafter. Results Overall, 245 patients underwent OAGB. Postoperative mortality was null, and early morbidity was observed in 14 (5.7%) patients. At 24 months, the percentage total weight loss (%TWL) was 43.2 ± 9, and percentage excess weight loss (%EWL) was 80 ± 15.7 (184 patients). At 60 months, %TWL was 41.9 ± 10.2, and %EWL was 78.1 ± 18.3 (79 patients). Conversion to Roux-en-Y gastric bypass was needed in three (1.2%) patients for reflux resistant to medical treatment. Six patients (2.4%) had reoperation for an internal hernia during follow-up. Anastomotic ulcers occurred in three (1.2%) patients. Only two patients (0.8%) underwent a second bariatric surgery for insufficient weight loss. Conclusion OAGB with a biliopancreatic limb of 150 cm is feasible and associated with sustained weight loss in the treatment of severe obesity with BMI > 50 kg/m2. Further randomized studies are needed to compare OAGB with other bariatric procedures in this setting. Graphical abstract

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Predictive Factors for Insufficient Weight Loss After Bariatric Surgery: Does Obstructive Sleep Apnea Influence Weight Loss?

Abstract: The presence of OSA does not individually impair weight loss after bariatric surgery.

Cited by 33 publications

References 19 publications

Bidirectional Relationships Between Weight Change and Sleep Apnea in a Behavioral Weight Loss Intervention

Bidirectional Relationships Between Weight Change and Sleep Apnea in a Behavioral Weight Loss Intervention

Weight Regain and Insufficient Weight Loss After Bariatric Surgery: Definitions, Prevalence, Mechanisms, Predictors, Prevention and Management Strategies, and Knowledge Gaps—a Scoping Review

Is One Anastomosis Gastric Bypass with a Biliopancreatic Limb of 150 cm Effective in the Treatment of People with Severe Obesity with BMI > 50?

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