volume 21, issue 10, P1387-1408 2002
DOI: 10.1002/sim.1118
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Abstract: In evaluating the risk of mortality or development of opportunistic infections in HIV-infected patients, the number of CD4 lymphocyte cells per cubic millimetre of blood is widely recognized as one of the best available predictors of such future events. However, its usefulness is limited by the incompleteness and variability of such CD4 measurements during follow-up. Because of these limitations, analysis of such data requires the missing measurements to be 'filled in' or the patients without them to be exclud…

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