volume 24, issue 3, P173-176 2009
DOI: 10.1590/s0102-86502009000300002
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Abstract: ABSTRACT Purpose:To study the effects of benzodiazepine midazolam in the coronary flow (Cflo), cardiac frequency (CF) and myocardial contractility in isolated hearts of rats subjected to ischemic preconditioning (IPC). Methods: 30 Wistar rats were used, undistinguished by gender. After anesthesia with ethyl ether, the hearts were put into perfusion (Krebs-Henseleit solution, 95% O 2 and 5% CO 2 , 37°C, 110-120mmHg), in disposable Langendorff type system. Five groups of six animals were constituted: GI-Control…

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