volume 8, issue 5, P958-977 2016
DOI: 10.18632/aging.100954
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Ilenia Segatto, Samuele Massarut, Robert Boyle, Gustavo Baldassarre, David Walker, Barbara Belletti

Abstract: Breast cancer is a frequent and treatable disease. However, when recurrent, breast cancer often becomes refractory to therapy and progresses into metastatic forms that are typically incurable. Thus, understanding and targeting the critical pathways underlying breast cancer recurrence is urgently needed to eradicate primary disease and achieve better prognosis. Recently, we have demonstrated that the ribosomal protein p70S6K is activated in residual breast cancer cells as a result of post-surgical inflammation …

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