Arch Derm Syphilol
 1920
DOI: 10.1001/archderm.1920.02350010028004
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Precancerous Dermatoses: The Further Course of Two Cases Previously Reported

John T. Bowen1
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Cited by 24 publications

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“…5) published in the Journal of Cutaneous Diseases in May 1912 10 . Amazingly, his observations were based on only two cases, although he did produce two follow‐up articles supporting his initial findings in 1915 and 1920 2,11,12 …”
Section: Contributions To Dermatology
mentioning
confidence: 95%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…5) published in the Journal of Cutaneous Diseases in May 1912 10 . Amazingly, his observations were based on only two cases, although he did produce two follow‐up articles supporting his initial findings in 1915 and 1920 2,11,12 …”
Section: Contributions To Dermatology
mentioning
confidence: 95%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…It is apparent to us today that the atypical nuclei, atypical mitotic figures, and neoplastic giant cells in the intraepidermal keratinocytes described and illustrated by Bowen, together with the clinical photographs, are those of squamous cell carcinoma in situ of the skin. In his original report and one that followed, 4 however, Bowen insisted that his patients were experiencing an inflammatory process. “[Histopathologically] there was no sign of distinct carcinomatous formation.” The concept at the time that inflammatory diseases (eg, tuberculosis and syphilis) could become malignant processes prompted Bowen to use the term precancerous dermatoses to describe his patients' condition.…”
mentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…The original description of SCCIS is attributed to JT Bowen in 1912 1 . A total of six patients (four men, two women) with dull red, firm, uneven, crusted and scaling patches and plaques, most commonly located on the trunk, were described by Bowen 2,3 and Darier 4 . Three patients had solitary lesions, and three had multiple lesions.…”
Section: History
mentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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