Prebiotics in infants for prevention of allergy

Abstract

Further research is needed before routine use of prebiotics can be recommended for prevention of allergy in formula fed infants. There is some evidence that a prebiotic supplement added to infant feeds may prevent eczema. It is unclear whether the use of prebiotic should be restricted to infants at high risk of allergy or may have an effect in low risk populations; or whether it may have an effect on other allergic diseases including asthma.

Cow’s milk-based beverage consumption in 1- to 4-year-olds and allergic manifestations: an RCT

“…These results are consistent with studies linking protection against AM with LCPUFAs [ 12 , 34 ], prebiotics [ 21 , 22 , 35 ] and β-glucan [ 28 , 36 , 37 ]. Dietary LCPUFAs were associated with less atopic dermatitis and wheezing [ 12 , 34 ], and amelioration of symptoms in asthmatic children [ 38 ].…”

Cow’s milk-based beverage consumption in 1- to 4-year-olds and allergic manifestations: an RCT

“…These results are consistent with studies linking protection against AM with LCPUFAs [ 12 , 34 ], prebiotics [ 21 , 22 , 35 ] and β-glucan [ 28 , 36 , 37 ]. Dietary LCPUFAs were associated with less atopic dermatitis and wheezing [ 12 , 34 ], and amelioration of symptoms in asthmatic children [ 38 ].…”

Prebiotics in infant nutrition: a critical appraisal

“…The same evaluation has been recently presented by Skorka et al [11] as regards growth and tolerance parameters, so confirming the same statements of all most recent reviews [79][80][81][82][83][84][85]. Then the following considerations will be focused only on the efficacy of prebiotics as functionally active ingredients of infant formula.…”

Immune‐mediated diseases and microbial exposure in early life

“…Another meta‐analyses found a protective effect of pro‐ and/or prebiotics on infant eczema but not allergic sensitization . Similar conclusions were made in two Cochrane meta‐analysis on probiotic and prebiotic supplement in early childhood. Comparison between studies is difficult due to large study heterogeneity both with respect to end‐point definition and characteristics of the intervention, such as choice of probiotic strain, and delivery and timing of the intervention.…”

Cow’s milk-based beverage consumption in 1- to 4-year-olds and allergic manifestations: an RCT

“…These results are consistent with studies linking protection against AM with LCPUFAs [ 12 , 34 ], prebiotics [ 21 , 22 , 35 ] and β-glucan [ 28 , 36 , 37 ]. Dietary LCPUFAs were associated with less atopic dermatitis and wheezing [ 12 , 34 ], and amelioration of symptoms in asthmatic children [ 38 ].…”

Prebiotics in infant nutrition: a critical appraisal

“…The same evaluation has been recently presented by Skorka et al [11] as regards growth and tolerance parameters, so confirming the same statements of all most recent reviews [79][80][81][82][83][84][85]. Then the following considerations will be focused only on the efficacy of prebiotics as functionally active ingredients of infant formula.…”

Immune‐mediated diseases and microbial exposure in early life

“…Another meta‐analyses found a protective effect of pro‐ and/or prebiotics on infant eczema but not allergic sensitization . Similar conclusions were made in two Cochrane meta‐analysis on probiotic and prebiotic supplement in early childhood. Comparison between studies is difficult due to large study heterogeneity both with respect to end‐point definition and characteristics of the intervention, such as choice of probiotic strain, and delivery and timing of the intervention.…”

Cow’s milk-based beverage consumption in 1- to 4-year-olds and allergic manifestations: an RCT

“…These results are consistent with studies linking protection against AM with LCPUFAs [ 12 , 34 ], prebiotics [ 21 , 22 , 35 ] and β-glucan [ 28 , 36 , 37 ]. Dietary LCPUFAs were associated with less atopic dermatitis and wheezing [ 12 , 34 ], and amelioration of symptoms in asthmatic children [ 38 ].…”

Prebiotics in infant nutrition: a critical appraisal

“…The same evaluation has been recently presented by Skorka et al [11] as regards growth and tolerance parameters, so confirming the same statements of all most recent reviews [79][80][81][82][83][84][85]. Then the following considerations will be focused only on the efficacy of prebiotics as functionally active ingredients of infant formula.…”

Immune‐mediated diseases and microbial exposure in early life

“…Another meta‐analyses found a protective effect of pro‐ and/or prebiotics on infant eczema but not allergic sensitization . Similar conclusions were made in two Cochrane meta‐analysis on probiotic and prebiotic supplement in early childhood. Comparison between studies is difficult due to large study heterogeneity both with respect to end‐point definition and characteristics of the intervention, such as choice of probiotic strain, and delivery and timing of the intervention.…”