DOI: 10.1002/chin.200739179
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Rene Peters, Christian Diolez, Alain Rolland et al.

Abstract: Alcohols as Masked Aldol Equivalents. -An efficient and scalable racemic as well as an asymmetric approach to the key building block, the DE ring fragment of homocamptothecin and derivatives such as the potent anticancer agent diflomotecan (I), are described. -(PETERS*, R.; DIOLEZ, C.; ROLLAND, A.; MANGINOT, E.; VEYRAT, M.; Heterocycles 72 (2007) 1, 255-273; Lab. Org. Chem., ETH Hoenggerberg, CH-8093 Zuerich, Switz.; Eng.) -M. Bohle