Potential role of oxidative stress in pathogenesis of benign prostatic hyperplasia in male dogs
Anna Domosławska‐Wyderska,
Sławomir Zduńczyk,
Agata Rafalska
Abstract:The pathogenesis of benign prostatic hyperplasia (BPH) in dogs is still not fully understood. Some studies suggest that oxidative stress may have a potential role in the pathogenesis of BPH in dogs. Age‐related hormonal changes may activate a chronic inflammatory response in the prostate. This causes the generation of reactive oxygen species (ROS) and results in oxidative stress. Excessive production of ROS results in DNA damage and hyperplastic transformation of prostatic cells. The use of antioxidants for im… Show more
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